Chronic kidney disease: a chronic challenge for imaging?

Chronic kidney disease: a chronic challenge for imaging?
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慢性肾脏病:成像的长期挑战?

DOI:
10.1007/s00330-023-09749-z
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发表时间:
2023
期刊:
影响因子:
5.9
通讯作者:
Wentland,AndrewL
Wentland,AndrewL
中科院分区:
医学2区
文献类型:
--
作者:
Wentland,AndrewL

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相似文献

影像学界迫切需要一种易于执行和现成的成像技术来评估慢性肾脏疾病(CKD)。慢性肾脏疾病影响了世界人口的很大一部分-超过8亿人[1]。CKD患者可能出现水肿或高血压。然而,许多CKD患者是无症状的,并通过血清肌酐升高或尿分析紊乱偶然发现。当肾脏萎缩和/或超声显示回声时,也可以在成像中偶然检测到CKD [2]。鉴于其可用性和易用性,超声检查是肾功能不全患者最常用的放射学技术。新发现的肾功能不全患者-通过血清肌酐升高-可能是急性或慢性的。超声提供的提示慢性的信息有限;慢性是由肾萎缩提示的。然而,这就是超声评估CKD的问题:评估是基本的-基本上提供了存在/不存在的二元答案。未评估CKD的严重程度。非常需要一种基于成像的技术,可以提供CKD的定量评估,以及早期发现实质变化。
The imaging community desperately needs an easy-to-perform and readily available imaging technique for evaluating chronic kidney disease (CKD). Chronic kidney disease affects a large proportion of the world population—greater than 800 million individuals [1]. Patients with CKD may present with edema or hypertension. Yet, many CKD patients are asymptomatic and are identified incidentally via elevated serum creatinine or derangements on urinalysis. CKD may also be detected incidentally on imaging when the kidneys have atrophied and/or are echogenic on ultrasound [2].Ultrasonography is the most common radiologic technique used in patients presenting with renal dysfunction given its availability and ease of use. Patients presenting with newly identified renal dysfunction—via elevated serum creatinine—may be acute or chronic. Ultrasound provides limited information indicative of chronicity; chronicity is suggested by renal atrophy. Therein, however, is the problem with the sonographic evaluation of CKD: the evaluation is rudimentary—providing essentially a binary answer of present/absent. The severity of CKD is not assessed. An imaging-based technique is much needed that can provide a quantitative assessment of CKD, as well as early detection of parenchymal changes.
DOI: --
发表时间: 2023
期刊: European Radiology
影响因子: 5.9
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