Quantitative developmental biology in vitro using micropatterning.
Quantitative developmental biology in vitro using micropatterning.
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DOI:
10.1242/dev.186387
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发表时间:
2021-08-01
期刊:
影响因子:
--
通讯作者:
Blin G
中科院分区:
文献类型:
--
作者:
Blin G
Micropatterning encompasses a set of methods aimed at precisely controlling the spatial distribution of molecules onto the surface of materials. Biologists have borrowed the idea and adapted these methods, originally developed for electronics, to impose physical constraints on biological systems with the aim of addressing fundamental questions across biological scales from molecules to multicellular systems. Here, I approach this topic from a developmental biologist's perspective focusing specifically on how and why micropatterning has gained in popularity within the developmental biology community in recent years. Overall, this Primer provides a concise overview of how micropatterns are used to study developmental processes and emphasises how micropatterns are a useful addition to the developmental biologist’s toolbox. Summary: This Primer introduces micropatterning as a tool to study development and discusses what we have learnt so far with this technique.
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