Inflammatory myopathies: issues in diagnosis and management.
Inflammatory myopathies: issues in diagnosis and management.
复制标题
炎症性肌病：诊断和治疗中的问题。
DOI：
10.1002/art.1790100308
复制
发表时间：
1997
期刊：
影响因子：
--
通讯作者：
Park,JH
中科院分区：
文献类型：
--
作者：
Olsen,NJ;Park,JH
磁共振成像和波谱技术已被证明在炎症性肌肉疾病的诊断和管理中具有实用性。但也许更重要的是MR研究对这些疾病的病理生理学有了新的认识，沿着的是关于自身抗体和细胞浸润的新的免疫学数据。炎症性肌肉疾病的病理亚群已经被鉴定，这表明，例如，PM和DM是不同的疾病，从而挑战了这些是相对同质的综合征的想法。从这些新发现中可能出现的对疾病发病机制的进一步见解可能允许鉴定病因因素和改进治疗方法。
The techniques of magnetic resonance imaging and spectroscopy have been shown to have utility in the diagnosis and management of inflammatory muscle diseases. But perhaps more important have been the new insights into the pathophysiology of these diseases which MR studies, along with new immunologic data on autoantibodies and cellular infiltrates, have afforded. Pathologic subsets of inflammatory muscle disorders have been identified, suggesting, for example, that PM and DM are distinct disorders, thereby challenging the idea that these are relatively homogeneous syndromes. Further insights into disease pathogenesis which are likely to emerge from these new findings may allow identification of etiologic factors and improved approaches to treatment.