Estimation of standard liver volume in Japanese living liver donors
Estimation of standard liver volume in Japanese living liver donors
复制标题
DOI：
10.1111/j.1440-1746.2006.04433.x
复制
发表时间：
2006-11-01
影响因子：
4.1
通讯作者：
Makuuchi, Masatoshi
中科院分区：
文献类型：
--
作者：
Hashimoto, Takuya;Sugawara, Yasuhiko;Makuuchi, Masatoshi
背景：标准肝体积（SLV）是成人活体肝移植中的一个重要概念。本研究的目的是重新评估和修改作者先前预测总肝体积（TLV）的公式。方法：用计算机断层扫描法测定301例日本活体供体的TLV。然后将该TLV与用既定公式计算的肝脏体积进行比较。分析了TLV与体表面积（BSA）等因素的相关性，确定了能更好地近似TLV的新方程（SLVn）。研究了TLV与slv差异的相关因素。结果：平均TLV为1196.3±221.0 cm(3)。Urata公式低估了TLV 17.6 cm(3)，其他公式高估了TLV 120.4 ~ 244.9 cm(3)。TLV可以用BSA近似；SLVn(厘米(3))= -404.8 + 961.3 x BSA (m (2), r2 = 0.58)。SLVn倾向于高估老年献血者的TLV，而低估瘦弱献血者的TLV。结论：提出了一个新的简便公式，可能更适合计算日本成人的TLV。这个公式可能对评估合适的移植物的大小有用。
Background: Standard liver volume (SLV) is an important concept in adult living liver donor transplantation. The purpose of this study was to re-evaluate and modify the authors' previous formula for predicting total liver volume (TLV).Methods: The TLV of 301 Japanese living donors was measured by computed tomography. This TLV was then compared with the liver volume calculated using established formulas. The correlation between TLV and several factors including body surface area (BSA) were analyzed and a new equation (SLVn) to better approximate TLV was determined. Factors related to the difference between TLV and SLVn were examined.Results: Average TLV was 1196.3 +/- 221.0 cm(3). Urata's formula underestimated TLV by 17.6 cm(3) and the other formulas overestimated it by 120.4-244.9 cm(3). TLV could be approximated by BSA; SLVn (cm(3)) = -404.8 + 961.3 x BSA (m(2), R-2 = 0.58). SLVn tended to overestimate the TLV of older donors and to underestimate TLV of thin donors.Conclusion: A new simple formula is presented that might be a better fit for calculating TLV in Japanese adults. This formula might be useful for evaluating the size of an adequate graft.