Examination of US puberty-timing data from 1940 to 1994 for secular trends: Panel findings
Examination of US puberty-timing data from 1940 to 1994 for secular trends: Panel findings
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DOI：
10.1542/peds.2007-1813d
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发表时间：
2008-02-01
期刊：
影响因子：
8
通讯作者：
Swan, Shanna H.
中科院分区：
文献类型：
--
作者：
Euling, Susan Y.;Herman-Giddens, Marcia E.;Swan, Shanna H.
如今的儿童，尤其是女孩，是否比20世纪中期更早进入青春期并进入青春期一直存在争议。基于现有数据的长期趋势分析受到不同人群、不同时期和使用不同方法的研究之间数据可比性的限制。因此，数据比较得出的结论并不一致。一个专家小组被要求评估证据的权重，以确定从1940年到1994年收集的数据是否足以表明或建立美国男孩或女孩青春期标志时间的长期趋势。大多数小组成员一致认为，数据足以表明女孩的乳房发育和月经初潮有提前的趋势，但其他女性青春期标志却没有。少数小组成员得出结论，目前关于任何标记的女孩青春期时间的数据都是不充分的。几乎所有的小组成员都得出结论，基于很少的研究和一些男性青春期标志的可靠性问题，目前男孩的数据不足以评估男性青春期发展的长期趋势。该小组一致认为，青春期时间的改变应被视为一种不良影响，尽管被认为是不良影响的变化程度没有得到评估。该小组建议(1)对现有的青春期时间数据进行进一步分析，以检查青春期事件时间序列的长期趋势和趋势；(2)开发青春期时间的生物标志物和区分脂肪和乳房组织的方法；(3)建立队列，在同一个体中纵向检查青春期标志物。
Whether children, especially girls, are entering and progressing through puberty earlier today than in the mid-1900s has been debated. Secular trend analysis, based on available data, is limited by data comparability among studies in different populations, in different periods of time, and using different methods. As a result, conclusions from data comparisons have not been consistent. An expert panel was asked to evaluate the weight of evidence for whether the data, collected from 1940 to 1994, are sufficient to suggest or establish a secular trend in the timing of puberty markers in US boys or girls. A majority of the panelists agreed that data are sufficient to suggest a trend toward an earlier breast development onset and menarche in girls but not for other female pubertal markers. A minority of panelists concluded that the current data on girls' puberty timing for any marker are insufficient. Almost all panelists concluded, on the basis of few studies and reliability issues of some male puberty markers, that current data for boys are insufficient to evaluate secular trends in male pubertal development. The panel agreed that altered puberty timing should be considered an adverse effect, although the magnitude of change considered adverse was not assessed. The panel recommended (1) additional analyses of existing puberty-timing data to examine secular trends and trends in the temporal sequence of pubertal events; (2) the development of biomarkers for pubertal timing and methods to discriminate fat versus breast tissue, and (3) establishment of cohorts to examine pubertal markers longitudinally within the same individuals.