Infectious Complications After Battlefield Injuries: Epidemiology, Prevention, and Treatment
Infectious Complications After Battlefield Injuries: Epidemiology, Prevention, and Treatment
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战场受伤后的感染性并发症：流行病学、预防和治疗
作者：
Heather C Yun;D. Blyth;C. Murray
回顾的目的最近的冲突导致了前所未有的比例的幸存者的复杂的战场伤害。这些患者易发生多重耐药微生物（MDRO）感染并发症。这些感染的流行病学，预防和治疗的描述，强调最近的literature.Recent FindingsData从创伤感染性疾病结局研究（TIDOS）队列已经揭示了27%的感染性并发症的发生率在创伤后撤离;这增加到50%在重症监护室。鲍曼不动杆菌-醋酸钙在伊拉克受伤的伤员中很常见，但在阿富汗的伤员中被其他产超广谱β-内酰胺酶的肠杆菌科和真菌所取代。感染预防包括短期窄谱预防性抗菌药物和感染控制;伤口感染预防的主要措施是清创和冲洗。许多感染的治疗主要是针对预期和恢复的病原体的手术和抗菌治疗。SummaryInfections战斗创伤后是常见和复杂的，需要多学科的方法来预防和护理。
Purpose of ReviewRecent conflicts have resulted in an unprecedented proportion of survivors of complex battlefield injuries. These patients are predisposed to infectious complications with multidrug-resistant organisms (MDROs). The epidemiology, prevention, and treatment of these infections are described, with emphasis on recent literature.Recent FindingsData from the Trauma Infectious Disease Outcomes Study (TIDOS) cohort have revealed a 27% rate of infectious complications in those evacuated after traumatic injury; this increases to 50% in the intensive care unit. Acinetobacter baumannii-calcoaceticus was common in casualties injured in Iraq, but was replaced by other extended-spectrum beta-lactamase-producing Enterobacteriaceae as well as fungi in casualties from Afghanistan. Prevention of infections includes short courses of narrow-spectrum prophylactic antimicrobials and infection control; the mainstay of wound infection prevention is debridement and irrigation. Treatment of many infections is primarily surgical and antimicrobial therapy directed against expected and recovered pathogens.SummaryInfections after combat trauma are common and complex, requiring a multidisciplinary approach to prevention and care.
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DOI：
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DOI：
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发表时间：
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