A Nurse Case Management HIV Prevention Intervention (Come As You Are) for Youth Experiencing Homelessness: Protocol for a Randomized Wait-list Controlled Trial.
A Nurse Case Management HIV Prevention Intervention (Come As You Are) for Youth Experiencing Homelessness: Protocol for a Randomized Wait-list Controlled Trial.
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护士案件管理艾滋病毒预防干预措施（您将与您一样），以实现无家可归的青年：随机等待名单对照试验的协议。
DOI：
10.2196/26716
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发表时间：
2021-05-21
影响因子：
1.7
通讯作者：
Calvo Armijo M
中科院分区：
文献类型：
--
作者：
Santa Maria D;Lightfoot M;Nyamathi A;Businelle M;Paul M;Quadri Y;Padhye N;Jones J;Calvo Armijo M
无家可归的年轻人比有住房的年轻人更有可能过早死亡、自杀、吸毒过量、怀孕、吸毒和精神疾病。然而，虽然无家可归的青年感染艾滋病毒的可能性是有住所青年的6至12倍，艾滋病毒感染率高达16%，但许多人无法获得所需的预防服务。尽管处境艰难，无家可归的青年仍对健康促进计划感兴趣，可以被招募并留在干预和研究中，并在计划量身定制并与他们相关时展示出改善的结果。该研究旨在比较护士病例管理艾滋病毒预防和护理干预的效果，题为“随你来”，与16至25岁无家可归青年的常规护理效果。本研究设计为2组随机等待名单对照试验。参与者（n=450）将被招募，并在干预后随访9个月，总研究期为12个月。Come As You Are将护士病例管理与基于智能手机的每日生态瞬间评估相结合，以制定可实时监测的参与者驱动的艾滋病毒预防行为目标。德克萨斯州休斯敦市的青年将从收容中心、收容所、街头拓展项目、青年服务组织和诊所招募。2018年11月获得机构审查委员会批准（人体受试者保护委员会，休斯顿德克萨斯大学健康科学中心）。第一位参与者于2019年11月入学。数据收集正在进行中。到目前为止，123名参与者已经同意参与这项研究，89人已经登记，15人已经完成了最后的随访。关于青年无家可归的艾滋病毒预防研究缺乏。需要新的和可扩展的干预措施，以解决行为和生物医学预防艾滋病毒的完整连续性。这项研究将确定一种个性化的流动艾滋病毒预防方法是否可以降低难以接触到的高风险青年流动人口的艾滋病毒风险。derr1 - 10.2196/26716
Youth experiencing homelessness are more likely than housed youth to experience premature death, suicide, drug overdose, pregnancy, substance use, and mental illness. Yet while youth experiencing homelessness are 6 to 12 times more likely to become infected with HIV than housed youth, with HIV prevalence as high as 16%, many do not access the prevention services they need. Despite adversities, youth experiencing homelessness are interested in health promotion programs, can be recruited and retained in interventions and research studies, and demonstrate improved outcomes when programs are tailored and relevant to them. The study aims to compare the efficacy of a nurse case management HIV prevention and care intervention, titled Come As You Are, with that of usual care among youth experiencing homelessness aged 16 to 25 years. The study is designed as a 2-armed randomized wait-list controlled trial. Participants (n=450) will be recruited and followed up for 9 months after the intervention for a total study period of 12 months. Come As You Are combines nurse case management with a smartphone-based daily ecological momentary assessment to develop participant-driven HIV prevention behavioral goals that can be monitored in real-time. Youth in the city of Houston, Texas will be recruited from drop-in centers, shelters, street outreach programs, youth-serving organizations, and clinics. Institutional review board approval (Committee for the Protection of Human Subjects, University of Texas Health Science Center at Houston) was obtained in November 2018. The first participant was enrolled in November 2019. Data collection is ongoing. To date, 123 participants have consented to participate in the study, 89 have been enrolled, and 15 have completed their final follow-up. There is a paucity of HIV prevention research regarding youth experiencing homelessness. Novel and scalable interventions that address the full continuum of behavioral and biomedical HIV prevention are needed. This study will determine whether a personalized and mobile HIV prevention approach can reduce HIV risk among a hard-to-reach, transient population of youth at high risk. DERR1-10.2196/26716
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