A mouse atlas of gene expression: Large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells
A mouse atlas of gene expression: Large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells
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DOI：
10.1073/pnas.0509455102
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发表时间：
2005-12-20
影响因子：
11.1
通讯作者：
Marra, MA
中科院分区：
文献类型：
--
作者：
Siddiqui, AS;Khattra, J;Marra, MA
我们分析了从72个文库中生成的855万个LongSAGE标签。从不同的小鼠组织制备每个LongSAGE文库。对数据的分析揭示了与现有基因数据集的广泛重叠，以及存在约24，000个先前未描述的基因组位点的证据。视觉皮层、胰腺、乳腺、植入前胚胎和胎盘含有最多的差异表达转录本，其中25%是以前未描述的位点。
We analyzed 8.55 million LongSAGE tags generated from 72 libraries. Each LongSAGE library was prepared from a different mouse tissue. Analysis of the data revealed extensive overlap with existing gene data sets and evidence for the existence of approximate to 24,000 previously undescribed genomic loci. The visual cortex, pancreas, mammary gland, preimplantation embryo, and placenta contain the largest number of differentially expressed transcripts, 25% of which are previously undescribed loci.