Early intervention in psychosis - The critical period hypothesis

Early intervention in psychosis - The critical period hypothesis
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DOI:
10.1192/s0007125000297663
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发表时间:
1998-06-01
影响因子:
10.5
通讯作者:
Jackson, C
Jackson, C
中科院分区:
医学1区
文献类型:
--
作者:
Birchwood, M;Todd, P;Jackson, C

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背景我们认为,早期阶段的精神病(包括未经治疗的精神病)是一个“关键时期”,其中(a)长期的结果是可预测的,和(B)生物,心理和社会心理的影响正在发展,并显示最大的plasticity.Method的证据。预测的结果和起源的患者的关键评价他们的psychoanalysed.Results的数据支持的概念的'高原效应',首先创造的汤姆McGlashan,这表明,恶化发生。它这样做积极在第一个2-3年;和关键的心理社会影响,包括家庭和心理反应的精神病和精神病服务,在此期间,development.Conclusions精神病的早期阶段提供了重要的机会,二级预防。我们概述了一个适合关键时期的干预原型,数据挑战了人们普遍认为的首发精神病是一种良性疾病,风险很小的假设。
Background We consider the evidence for the proposition that the early phase of psychosis (including the period of untreated psychosis) is a 'critical period' in which (a) long-term outcome is predictable, and (b) biological, psychological and psychosocial influences are developing and show maximum plasticity.Method First-episode prospective studies. predictors of outcome and the genesis of patients' key appraisals of their psychosis are reviewed.Results The data support the notion of the 'plateau effect', first coined by Tom McGlashan, which suggested that where deterioration occurs. it does so aggressively in the first 2-3 years; and that critical psychosocial influences, including family and psychological reactions to psychosis and psychiatric services, develop during this period.Conclusions The early phase of psychosis presents important opportunities for secondary prevention. We outline a prototype of intervention appropriate to the critical period.The data challenge the widely held assumption that first-episode psychosis is a benign illness posing little risk.