Advances in the treatment of rotator cuff lesions by cytokines.
Advances in the treatment of rotator cuff lesions by cytokines.
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DOI：
10.2741/4499
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发表时间：
2017
期刊：
影响因子：
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通讯作者：
Genbin Wu;P. Xu;Peng Wu;K. Hu;Yeqin Sun;B. Cheng;Yong Lu
中科院分区：
文献类型：
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作者：
Genbin Wu;P. Xu;Peng Wu;K. Hu;Yeqin Sun;B. Cheng;Yong Lu
肩袖撕裂是最常见的肩部问题之一，通常需要手术治疗。用于修复断裂肌腱的治疗方法包括缝合、自体移植、同种异体移植和合成假体。尽管迄今为止手术治疗已取得显着改善，但肩部病理学仍然对骨科手术构成挑战，主要是因为这些损伤通常对治疗反应不佳并且需要长期康复。最近的注意力集中在几种可以增强肌腱愈合功能的生物途径上，从而导致了参与该过程的生长因子的鉴定。在这篇综述中，我们讨论了近年来发表的有关这些生长因子及其在肩袖愈合中的作用的研究。
Rotator cuff tears are one of the most common shoulder problems that usually require operative treatments. Therapeutic options used to repair ruptured tendons have consisted of suture, autografts, allografts, and synthetic prostheses. Although surgical treatments have improved dramatically up to now, shoulder pathology is still challenging to orthopedic surgery primarily because these injuries often respond poorly to treatment and require prolonged rehabilitation. Recent attention has focused on several biologic pathways which can augment function to tendon healing, consequently leading to the identification of growth factors involved in this process. In this review, we discuss the studies published in these few years about these growth factors and their role in rotator cuff healing.