Role of growth factors in control of pancreatic beta cell mass: focus on betatrophin.
Role of growth factors in control of pancreatic beta cell mass: focus on betatrophin.
复制标题
生长因子在控制胰腺 β 细胞质量中的作用：关注β-营养因子。
DOI：
10.1097/mop.0000000000000110
复制
发表时间：
2014
影响因子：
3.6
通讯作者：
Rhoads,DavidB
中科院分区：
文献类型：
--
作者：
Levitsky,LynneL;Ardestani,Goli;Rhoads,DavidB
许多内分泌和旁分泌因子，其中betatrophin是最新描述的，在小鼠模型中增加β细胞质量。这些因子，包括betatrophin，都没有在临床研究中表现出相同的活性。这可能反映了小鼠和人类β细胞再生途径的深刻物种差异。
Many endocrine and paracrine factors, of which betatrophin is the newest described, increase beta cell mass in murine models. None of these factors, including betatrophin, have displayed the same activity in clinical studies. This may reflect a profound species difference in beta cell regeneration pathways in mice and humans.