Conceptual Design and Prototyping for a Primate Health History Knowledge Model.
Conceptual Design and Prototyping for a Primate Health History Knowledge Model.
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DOI：
10.1007/978-3-030-71051-4_40
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发表时间：
2021
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灵长类动物模型对于理解人类状况非常重要，特别是在衰老，病理学，适应和进化的研究中。然而，如何整合来自多个学科的数据，并使它们相互兼容，以进行数据挖掘和深入研究一直是一个挑战。在一个长期项目中，我们已经开始了一项合作研究奋进，以检查圣地亚哥岛自由放养的恒河猴群体的健康史，并建立一个知识模型，用于环境和遗传对骨骼发育，衰老和病理的影响的人类学和生物医学/翻译研究。本文讨论了概念设计，以及原型的这个模型和相关的图形用户界面，以及这些将如何帮助未来的科学查询和研究。
Primate models are important for understanding human conditions, especially in studies of ageing, pathology, adaptation, and evolution. However, how to integrate data from multiple disciplines and render them compatible with each other for datamining and in-depth study is always challenging. In a long-term project, we have started a collaborative research endeavor to examine the health history of a free-ranging rhesus macaque colony at Cayo Santiago, and build a knowledge model for anthropological and biomedical/translational studies of the effects of environment and genetics on bone development, aging, and pathologies. This paper discusses the conceptual design as well as the prototyping of this model and related graphical user interfaces, and how these will help future scientific queries and studies.