ASSESSMENT OF REGIONAL CEREBRAL BLOOD-FLOW (RCBF) IN STROKE USING SPECT AND N-ISOPROPYL-(I-123)-PARA-IODOAMPHETAMINE (IMP)
ASSESSMENT OF REGIONAL CEREBRAL BLOOD-FLOW (RCBF) IN STROKE USING SPECT AND N-ISOPROPYL-(I-123)-PARA-IODOAMPHETAMINE (IMP)
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DOI：
10.1161/01.str.15.1.40
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发表时间：
1984-01-01
期刊：
影响因子：
8.3
通讯作者：
CLOUSE, ME
中科院分区：
文献类型：
--
作者：
HILL, TC;MAGISTRETTI, PL;CLOUSE, ME
应用单光子发射计算机断层扫描(SPECT)和N-异丙基-123P-碘苯丙胺(IMP)对有急性卒中体征和症状的患者进行局部脑血流检测。急性脑梗塞患者(25例)在1周内同时进行IMP脑灌注检查和CT扫描；22例为阳性，3例为阴性。在22例血流灌注检查阳性的患者中，6例最初CT检查为阴性。在16例CT检查异常的患者中，8例显示的水肿区小于IMP研究中记录的灌注缺损区，8例的水肿区大小与灌注区的缺损区大致相同。在3例IMP检查正常的患者中，2例CT检查正常，1例CT检查阳性，显示3 mm腔隙性脑梗塞。
Regional cerebral blood flow was assessed in patients with signs and symptoms of acute stroke using single-photon emission computed tomography (SPECT) and N-isopropyl I-123 p-iodoamphetamine (IMP). Patients (25) with acute cerebral infarction had both IMP brain perfusion studies and CT scans performed within 1 wk of each other; 22 had positive and 3 had negative perfusion studies. Of the 22 patients who had positive perfusion studies, 6 had negative CT studies initially. In the 16 patients who had abnormal CT studies, 8 of the studies depicted areas of edema that were smaller than the perfusion deficits noted on the IMP studies and 8 had areas of edema that were approximately equal in size to the perfusion defect. Of the 3 patients with normal IMP studies, 2 had normal CT studies and 1 had a positive CT study showing a 3-mm lacunar infarction.