A Pilot Trial Examining African American and White Responses to Algorithm-Guided Smoking Cessation Medication Selection in Persons Living with HIV
A Pilot Trial Examining African American and White Responses to Algorithm-Guided Smoking Cessation Medication Selection in Persons Living with HIV
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DOI：
10.1007/s10461-016-1634-0
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发表时间：
2017-07-01
影响因子：
4.4
通讯作者：
Cropsey, Karen L.
中科院分区：
文献类型：
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作者：
Valera, Pamela;McClernon, F. Joseph;Cropsey, Karen L.
基于药物的治疗（AT）可能是一种有效的临床工具，以帮助艾滋病毒临床医生处方药物治疗，以增加艾滋病毒感染者（PLWH）的戒烟。AT的初步结果表明，随着时间的推移，戒烟自我效能和药物利用率显着增加，每天吸烟量下降。考虑到历史上的种族差异，目前还不清楚非裔美国人和白色吸烟者是否会从这种干预中同样受益。因此，本研究的目的是检查种族差异的反应AT指导戒烟的非裔美国人和白色吸烟者感染艾滋病毒。100名PLWH吸烟者（n = 100）被随机分配接受AT指导的戒烟或治疗作为治疗（TAU），其中包括指导参与者在准备戒烟尝试时与提供者谈论戒烟帮助。参与者是非洲裔美国人（75%）和白色（25%）和大多数男性（71%）从未结婚（56%）。与基线时的白色吸烟者相比，非裔美国人吸烟较少，更有可能吸烟含薄荷醇的香烟。与白色吸烟者相比，非裔美国人随着时间的推移增加了其他烟草产品（雪茄/小雪茄）的使用。观察到种族和戒烟目标之间存在显著的相互作用，报告完全戒烟为目标的白色吸烟者戒烟率较高，而报告完全戒烟以外目标的非裔美国人戒烟率较高。在对PLWH非裔美国人吸烟者应用基于算法的干预措施时，应考虑戒烟尝试期间雪茄/小雪茄的使用增加以及完全戒烟以外的目标。
Algorithm-based treatments (AT) may be an effective clinical tool to aid HIV clinicians in prescribing pharmacotherapy to increase smoking cessation among people living with HIV (PLWH). Initial results from AT indicated significant increases in abstinence self-efficacy and medication utilization and declines in cigarettes smoked per day across time. Given historical racial disparities, it is unclear if both African Americans and White smokers would benefit equally from this type of intervention. Thus, the aim of this study was to examine racial differences in response to AT guided smoking cessation for African American and White smokers living with HIV. One hundred PLWH smokers (n = 100) were randomized to receive either AT guided smoking cessation or Treatment as Usual (TAU) which consisted of instructing participants to talk to a provider about smoking cessation assistance when ready to make a quit attempt. Participants were African American (75%) and White (25%) and majority men (71%) who had never been married (56%). African Americans smoked fewer cigarettes and were more likely to smoke mentholated cigarettes compared to White smokers at baseline. African Americans increased their use of other tobacco products (cigars/cigarillos) over time relative to White smokers. A significant interaction between race and quit goal was observed, with White smokers who reported complete abstinence as their goal having higher quit rates, while African Americans who reported a goal other than complete abstinence demonstrating higher quit rates. The increased use of cigars/cigarillos during quit attempts as well as having a goal other than complete abstinence should be considered when applying algorithm based interventions for PLWH African American smokers.