Congenital Ptosis and Amblyopia

Congenital Ptosis and Amblyopia
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DOI:
10.3928/01913913-20100308-08
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发表时间:
2010-03-01
影响因子:
1.2
通讯作者:
Dogan, Omer Kamil
Dogan, Omer Kamil
中科院分区:
医学4区
文献类型:
--
作者:
Oral, Yesim;Ozgur, Ozlen Rodop;Dogan, Omer Kamil

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目的:目的:探讨先天性上睑下垂患者弱视的发生率及病因。方法:对72例83眼先天性上睑下垂患者进行弱视发生率及病因分析。患者年龄范围为10个月至70岁。弱视定义为最佳矫正视力0.7或更低。在一个完整的眼科检查后,确定上睑下垂和提上睑肌功能,并确定以下弱视因素:屈光不正,屈光参差和斜视。结果:先天性上睑下垂83眼中,轻度5眼(6%),中度26眼(31%),重度52眼(63%)。斜视17眼(20%)。4岁以下上睑下垂儿童83只眼中,10只眼视力不能确定。其余73只眼弱视总发生率为48%。在这些弱视患者中,54%有屈光不正,如屈光参差或屈光不正,20%有斜视伴或不伴屈光不正,26%的弱视仅归因于上睑下垂。结论:对屈光不正、斜视等弱视因素应及早发现和治疗,对瞳孔轴阻塞伴重度上睑下垂者应尽早手术治疗,以防止刺激剥夺性弱视的发生。
Purpose: To investigate the incidence and causes of amblyopia in congenital ptosis.Methods: The frequency and causes of amblyopia were evaluated in 83 eyes of 72 patients with congenital ptosis. Patient ages ranged between 10 months and 70 years. Amblyopia was defined as best-corrected visual acuity of 0.7 or less. After a complete ophthalmologic examination, the amount of ptosis and levator function was determined and the following arnblyogenic factors were identified: ametropia, anisometropia, and strabismus. In cases with no other reason for amblyopia, stimulus deprivation amblyopia due to ptosis was assumed.Results:The amount of ptosis was mild in 5 (6%), moderate in 26 (31%), and severe in 52 (63%) of 83 eyes with congenital ptosis. Strabismus was present in 17 (20%) eyes. Visual acuity could not be determined in 10 of 83 eyes with ptosis in children younger than 4 years. The overall incidence of amblyopia in the remaining 73 eyes was 48%. Of those patients with amblyopia, 54% had refactive errors such as anisometropia or ametropia, 20% had strabismus with or without refractive errors, and 26% had amblyopia solely attributed to ptosis. When all eyes with ptosis were included, the rate of stimulus deprivation amblyopia was 12% and all of these eyes had severe ptosisConclusion: Early detection and treatment of amblyogenic factors such as refractive errors and strabismus is recommended and, when the pupillary axis is occluded with severe ptotic eyelids, surgery should be performed as soon as possible to prevent stimulus deprivation amblyopia.