Epidemiology of Uveitis in a Spanish Region: Prevalence and Etiology
Epidemiology of Uveitis in a Spanish Region: Prevalence and Etiology
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DOI：
10.1080/09286586.2020.1815802
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发表时间：
2020-09-07
影响因子：
1.8
通讯作者：
Munoz-Fernandez, S.
中科院分区：
文献类型：
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作者：
Garcia-Aparicio, A.;Alonso Martin, L.;Munoz-Fernandez, S.
目的评估葡萄膜炎的患病率，并描述其病因和解剖模式的基础上进行的人口研究在西班牙地区。材料和方法进行了一项横断面、描述性、基于人群的多中心研究。选择标准包括诊断为葡萄膜炎。所有数据均来自病历中的现有信息。从研究之日至次年年底，在参与中心收集所有诊断为葡萄膜炎的病例的临床信息，无论其病因如何。所有患者都接受了完整的眼科检查，包括视力评估、生物显微镜检查、压平张力计和间接检眼镜检查。结果共登记葡萄膜炎患者389例。患病率为58.7（95%置信区间[CI] 53.0-64.9）。平均年龄为47.0 ± 20.6岁，57.8%为女性。最常见的解剖学模式是前葡萄膜炎（54.2; 95% CI 48.1-60.8）。对于成人，特发性组构成了最高的患病率（31.7; 95% CI：27.1-36.9），而自身免疫性病因在儿童中最常见（10.6; 95% CI：5.8-17.7）。结论这项以人群为基础的研究结果提供了一个代表性的估计葡萄膜炎在西班牙这一地区的规模。
Objective To estimate the prevalence of uveitis and to describe its etiologic and anatomical patterns based on a population study carried out in a Spanish region. Material and methods A cross-sectional, descriptive, population-based multicenter study was conducted. The selection criteria consisted of having a diagnosis of uveitis. All data were collected from existing information in medical records. Clinical information was collected in all cases that had a diagnosis of uveitis, regardless of its etiology, in participating centers from the date of the study to the end of the following year. All patients underwent a complete ophthalmological examination, which included assessment of their visual acuity, biomicroscopy, applanation tonometry, and indirect ophthalmoscopy. Results During the study, 389 cases of uveitis were registered. The prevalence was 58.7 (95% confidence interval [CI] 53.0-64.9). The mean age was 47.0 +/- 20.6 years and 57.8% were women. The most prevalent anatomical pattern was anterior uveitis (54.2; 95% CI 48.1-60.8). For adults, the idiopathic group constituted the highest prevalence (31.7; 95% CI: 27.1-36.9), while autoimmune etiology was most frequent for children (10.6; 95% CI: 5.8-17.7). Conclusion The results of this population-based study offer a representative estimate of the magnitude of uveitis in this area of Spain.