Development of a stepwise [3+3] annelation to functionalized piperidines
Development of a stepwise [3+3] annelation to functionalized piperidines
复制标题
DOI：
10.1021/ol050965t
复制
发表时间：
2005-07-07
期刊：
影响因子：
5.2
通讯作者：
Harrity, JPA
中科院分区：
文献类型：
--
作者：
Goodenough, KM;Raubo, P;Harrity, JPA
通过Grignard加成-环化反应的逐步形式的[3 + 3]环加成序列导致大大改进的哌啶合成。该方法在氮丙啶底物和TMM等效物两者中提供改进的灵活性。
A stepwise formal [3 + 3] cycloaddition sequence via a Grignard addition-cyclization reaction leads to a much improved piperidine synthesis. This methodology provides improved flexibility in both the aziridine substrate and TMM equivalent.