Cobalt-catalyzed cross-dehydrogenative coupling reaction in water by visible light
Cobalt-catalyzed cross-dehydrogenative coupling reaction in water by visible light
复制标题
可见光下钴催化的水中交叉脱氢偶联反应
DOI：
10.1021/ol503744a
复制
发表时间：
2015
期刊：
影响因子：
5.2
通讯作者：
Wu Li-Zhu
中科院分区：
文献类型：
--
作者：
Wu Cheng-Juan;Zhong Jian-Ji;Meng Qing-Yuan;Lei Tao;Gao Xue-Wang;Tung Chen-Ho;Wu Li-Zhu
通过使用催化量的CoCl 2与dmgH（丁二酮肟）作为配体原位形成光敏剂，在水介质中开发了一种高度选择性、高效且环境友好的可见光介导的交叉脱氢偶联（CDC）反应。分别涉及Csp 3与Csp、Csp 2和Csp 3的所需交叉偶联C-C键仅以高产率实现，而不形成任何其他副产物。
By using catalytic amount of CoCl2with dmgH (dimethylglyoxime) as ligand to form a photosensitizer in situ, a highly selective, efficient, and environmentally benign visible light mediated cross-dehydrogenative coupling (CDC) reaction has been developed in aqueous medium. The desired cross-coupling C–C bonds that involve Csp3with Csp, Csp2, and Csp3, respectively, were achieved exclusively in high yields without formation of any other byproduct.