RETINOL TRANSFER ACROSS AND BETWEEN PHOSPHOLIPID-BILAYER MEMBRANES
RETINOL TRANSFER ACROSS AND BETWEEN PHOSPHOLIPID-BILAYER MEMBRANES
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DOI：
10.1016/0005-2736(88)90438-5
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发表时间：
1988-10-06
期刊：
影响因子：
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通讯作者：
JOHANNESSON, G
中科院分区：
文献类型：
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作者：
FEX, G;JOHANNESSON, G
使用单层脂质体和红细胞在体外研究了视黄醇跨双层膜和双层膜之间的转移。视黄醇在磷脂双层膜中的跨膜运动是一个自发的、快速的过程，半衰期小于30 s。脂质体之间和脂质体与红细胞之间的视黄醇转移也是一个自发和快速的过程，半衰期小于10分钟。结果表明，视黄醇在细胞内的运输可能不需要特定的转移蛋白的参与。
The transfer of retinol across and between bilayer membranes was studied in vitro using unilamellar liposomes and erythrocytes. Transmembrane movement of retinol in phospholipid bilayer membranes was a spontaneous and rapid process with a halflife of less than 30 s. Retinol transfer between liposomes and between liposomes and erythrocytes was also a spontaneous and rapid process with a halflife of less than 10 min. The results suggest that retinol transport in the cell might not need the participation of specific transfer proteins.