Shared Trans-ancestry Genetic Etiology between Panic Disorder and Anxiety Disorders.
Shared Trans-ancestry Genetic Etiology between Panic Disorder and Anxiety Disorders.
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恐慌症和焦虑症之间共有的跨祖先遗传病因学。
DOI：
10.1111/pcn.13214
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发表时间：
2021
期刊：
影响因子：
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通讯作者：
Shioiri T
中科院分区：
文献类型：
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作者：
Ohi K;Otowa T;Shimada M;Sugiyama S;Muto Y;Tanahashi S;Kaiya H;Nishimura F;Sasaki T;Tanii H;Shioiri T
摘要GLO: 82I/01jun21: pcn13214-fig-0001。欧洲焦虑症的多基因风险评分（焦虑神经遗传学研究[ANGST]， iPSYCH, UK Biobank [UKBB]，以及这些全基因组关联研究[META]）在每个阈值（PT截止）上对日本患者恐慌障碍（PD）风险的影响。惊恐障碍（PD）是一种焦虑障碍，具有一定的遗传性。从欧洲焦虑症UKBB患者中获得的PRS在日本PD患者中明显高于HC患者(图。[摘自文章]《精神病学与临床神经科学》版权归Wiley-Blackwell所有，未经版权所有者明确书面许可，其内容不得复制或通过电子邮件发送到多个网站或发布到listserv。但是，用户可以打印、下载或通过电子邮件发送文章供个人使用。这篇摘要可以删节。对副本的准确性不作任何保证。用户应参考资料的原始出版版本以获取完整摘要。版权适用于所有摘要。
Abstract GLO: 82I/01jun21: pcn13214-fig-0001. jpg PHOTO (COLOR): 1 Effects of polygenic risk scores for European anxiety disorders (Anxiety NeuroGenetics Study [ANGST], iPSYCH, UK Biobank [UKBB], and a meta-analysis of these genome-wide association studies [META]) at each threshold (PT cutoff) on the risk of panic disorder (PD) in Japanese patients. Panic disorder (PD), an anxiety disorder, is modestly heritable. The PRS obtained from the European anxiety UKBB patients were significantly higher in Japanese patients with PD than in HC (Fig.[Extracted from the article]Copyright of Psychiatry & Clinical Neurosciences is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. Copyright applies to all Abstracts.