Selective C-S Bond Formation via Fe-Catalyzed Allylic Substitution
Selective C-S Bond Formation via Fe-Catalyzed Allylic Substitution
复制标题
DOI：
10.1021/ol901297s
复制
发表时间：
2009-08-06
期刊：
影响因子：
5.2
通讯作者：
Plietker, Bernd
中科院分区：
文献类型：
--
作者：
Jegelka, Markus;Plietker, Bernd
与C-O键和C-N键的形成相反，通过过渡金属配合物选择性地形成C-S键只是最近才成为研究的中心。考虑到官能团中的硫原子可以具有对应于不同化学性质和反应组合的不同氧化水平的事实，这在一定程度上是令人惊讶的。在本文中，我们希望传达区域选择性Fe催化的烯丙基磺化，其允许以良好至优异的产率制备各种手性芳基烯丙基砜。
In contrast to the formation of C-O and C-N bonds it was only recently that the selective C-S bond formation by means of transition metal complexes moved more into the center of research. This is somewhat surprising given the fact that the sulfur atom in a functional group can possess different oxygenation levels which correspond to different chemical properties and reaction portfolios, Herein we wish to communicate a regioselective Fe-catalyzed allylic sulfonation that allows for the preparation of various chiral aryl allyl sulfones In good to excellent yields.