Low concentrations, potential ecological consequences: synthetic estrogens alter life-history and demographic structures of aquatic invertebrates.
Low concentrations, potential ecological consequences: synthetic estrogens alter life-history and demographic structures of aquatic invertebrates.
复制标题
DOI：
10.1016/j.envpol.2013.03.038
复制
发表时间：
2013-07
影响因子：
8.9
通讯作者：
M. S. Souza;P. Hallgren;E. Balseiro;L. Hansson
中科院分区：
文献类型：
--
作者：
M. S. Souza;P. Hallgren;E. Balseiro;L. Hansson
避孕药物现在在地球仪的水生环境中发现。特别是，17α-乙炔基甜菜碱（EE 2）即使在低浓度下也可能发挥作用，例如在自然生态系统中记录的浓度。我们评价了EE 2对海洋和淡水群落中常见的桡足类--剑水蚤和哲水蚤的生理效应。我们使用了三种EE 2浓度，并评估其对不同生理终点活性的影响：乙酰胆碱酯酶（神经传递），谷胱甘肽S-转移酶（解毒系统）和Caspase-3（细胞凋亡）。EE 2对解毒和凋亡系统有明显的作用，但在环境剂量下对AChE无影响。我们的研究结果表明，EE 2暴露影响不同的桡足类生理终点，改变蜕皮过程，成人招聘哲水蚤和哲水蚤剑水蚤的比例。这种潜在的生理过程的生态后果可能会影响，因为生活史的人口和社区结构，这代表了一个新的方面，这种外源性物质在自然系统中。
Contraceptive drugs are nowadays found in aquatic environments around the globe. Particularly, 17α-ethinylestradiol (EE2) may act even at low concentrations, such as those recorded in natural ecosystems. We evaluated the physiological effects of EE2on cyclopoids and calanoids, common copepods in both marine and freshwater communities. We used three EE2concentrations and assessed its impact on activity of different physiological endpoints: Acetylcholinesterase (neurotransmission), Glutathione S-transferase (detoxifying system), and Caspase-3 (apoptosis). While EE2exerts, distinctive effect on detoxifying and apoptotic systems, no effect on AChE was observed at environmental doses. Our results show that EE2exposure affects differently copepod physiology endpoints, altering moulting process, adult recruitment in calanoids and calanoid to cyclopoid ratio. The ecological consequences of this underlying physiological process may affect since life history to population and community structures, and this represent a new aspects of this xenobiotic in natural systems.