Iron intake and iron status in breastfed infants during the first year of life

Iron intake and iron status in breastfed infants during the first year of life
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DOI:
10.1016/j.clnu.2010.05.002
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发表时间:
2010-12-01
期刊:
影响因子:
6.3
通讯作者:
Kersting, Mathilde
Kersting, Mathilde
中科院分区:
医学1区
文献类型:
--
作者:
Dube, Katharina;Schwartz, Jana;Kersting, Mathilde

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背景与目的:母乳喂养的婴儿可能特别容易缺铁,因为母乳中的铁含量很低。在对补充喂养试验数据的二次分析中,检查了铁状态的指标,特别关注在出生后头4个月完全母乳喂养的婴儿铁状态的发展。方法:在这项对随机对照试验数据的回顾性分析中,婴儿根据其出生后头4个月的主要牛奶饮食进行分层,将母乳喂养的婴儿亚组(BM组,n = 53)与喂养(铁强化)配方奶粉的婴儿亚组(F组,n = 23)进行比较。膳食铁的摄入量和指标的铁的状态进行了分析,在4个月的年龄(在充分的牛奶喂养期),并在7和10个月的年龄在补充喂养期。结果:铁的摄入量是低的BM组,范围低于整个补充喂养期的膳食参考摄入量,与(估计)生物可利用铁的摄入量只是刚刚达到参考要求。在4个月时,铁缺乏(ID,铁蛋白
Background & aims: Breastfed infants may be at particular risk for iron deficiency because breast milk is low in iron. In a secondary analysis of data from a complementary feeding trial, indicators of iron status were examined, with particular focus on the development of iron status in those infants who were fully breastfed during the first 4 months of life.Methods: In this retrospective analysis of data from a randomized controlled trial infants were stratified according to their predominant milk diet during the first 4 months of life, a subgroup of breastfed infants (group BM, n = 53) were compared with a subgroup of infants fed (iron-fortified) formula (group F, n = 23). Dietary iron intake and indicators of iron status were analysed at 4 months of age (during the full milk feeding period), and during the complementary feeding period at 7 and 10 months of age.Results: Iron intake was low in the BM group, ranging below the Dietary Reference Intakes throughout the complementary feeding period, with the (estimated) bioavailable iron intake only just achieving the reference requirements. At 4 months, iron deficiency (ID, Ferritin