Validity of the time trade-off and standard gamble methods of utility assessment in retinal patients
Validity of the time trade-off and standard gamble methods of utility assessment in retinal patients
复制标题
视网膜患者效用评估的时间权衡和标准赌博方法的有效性
DOI：
--
复制
发表时间：
2002
影响因子：
4.1
通讯作者：
G. Shah
中科院分区：
文献类型：
--
作者：
Sanjay Sharma;G. Brown;Melissa M. Brown;H. Hollands;R. Robins;G. Shah
目的：评估视网膜疾病患者效用评估的时间权衡（TTO）和标准参考赌博（SRG）技术的有效性。一个符合条件的患者的横截面进行了研究，有效性通过他们的关系与两个逻辑结构，视力和分数的视觉功能14（VF-14）指数。方法：本研究包括合格的患者提出的三级视网膜设施谁完成了采访。所有患者的最佳矫正视力为20/40或至少一只眼睛更差。TTO和SRG工具，以及VF-14问卷，通过标准化访谈进行管理。还收集了人口统计学和临床（包括Snellen视力）信息。结果：323例患者符合这些研究标准。多变量分析中TTO效用的显著预测因素是较好视力眼的视力（p<0.01）和VF-14评分（p<0.01）。标准Gamble效用的显著预测因子还包括视宁更佳眼的视力（p<0.01）和VF-14评分（p<0.05）。结论：当针对更好视力的视力和VF-14评分进行评估时，标准gamble和TTO方法都表现出很强的有效性。
Aim: To assess the validity of the time trade-off (TTO) and standard reference gamble (SRG) techniques of utility assessment in patients with retinal disease. A cross section of eligible patients was studied and validity was determined through their relation with two logical constructs, visual acuity and scores from the Visual Function 14 (VF-14) index. Methods: The study consisted of eligible patients presenting to a tertiary retinal facility who completed an interview. All patients had best corrected vision of 20/40 or worse in at least one eye. TTO and SRG utilities, as well as a VF-14 questionnaire, were administered through a standardised interview. Demographic and clinical (including Snellen visual acuity) information was also collected. Results: 323 patients met these study criteria. Significant predictors of TTO utilities in the multivariate analysis were vision in the better seeing eye (p<0.01) and VF-14 scores (p<0.01). Significant predictors of standard gamble utilities were also vision in the better seeing eye (p<0.01) and VF-14 scores (p<0.05). Conclusion: Both the standard gamble and TTO methods demonstrate strong validity when evaluated against visual acuity in the better seeing eye and the VF-14 score.