Correlation of quantitative light-induced fluorescence and optical coherence tomography applied for detection and quantification of early dental caries

Correlation of quantitative light-induced fluorescence and optical coherence tomography applied for detection and quantification of early dental caries
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DOI:
10.1117/1.1606685
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发表时间:
2003-10-01
影响因子:
3.5
通讯作者:
Jackson, DA
Jackson, DA
中科院分区:
医学3区
文献类型:
--
作者:
Amaechi, BT;Podoleanu, A;Jackson, DA

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脱矿后牙釉质的荧光损失与脱矿过程中矿物质损失的量相关。在生产人工龋齿的脱矿过程中,研究了通过定量光诱导荧光 (QLF) 测量的荧光损失与通过多功能正面光学相干断层扫描 (OCT) 系统测量的反射率损失之间的相关性。我们使用的 OCT 系统可以收集 A 扫描(反射率与深度)、B 扫描(纵向图像)和 C 扫描(正面图像)。样品的功率为 250 μW,波长 lambda = 850 nm,空气中的深度分辨率为 16 μm。 A 扫描显示反射率与穿透牙齿组织深度的关系,用于反射率损失的定量分析。结果表明,随着脱矿时间的增加,牙釉质的荧光辐射亮度和反射率均降低。QLF测量的荧光损失百分比与OCT测量的反射率损失百分比之间观察到线性相关。结论是,通过 OCT 测量,脱矿过程中牙釉质反射率的下降可能与脱矿过程中矿物质损失量有关。 (C) 2003 年光电仪器工程师协会。
Fluorescence loss in enamel following demineralization has been correlated with the amount of mineral lost during the demineralization. The correlation between fluorescence loss measured by quantitative light-induced fluorescence (QLF) and the reflectivity loss measured by a versatile en face optical coherence tomography (OCT) system was investigated in a demineralization process to produce artificial dental caries. We used an OCT system that can collect A-scans (reflectivity versus depth), B-scans (longitudinal images), and C-scans (en face images). The power to the sample was 250 muW, the wavelength lambda = 850 nm, and the depth resolution in air 16 mum. A-scans, which show the profile of the reflectivity versus the depth of penetration into the tooth tissue, were used for quantitative analysis of the reflectivity loss. The results have shown that both the fluorescence radiance and reflectivity of the enamel decrease with increasing demineralization time A linear correlation was observed between the percentage of fluorescence loss measured by QLF and the percentage of reflectivity loss measured by OCT. It was concluded that the decrease in reflectivity of the enamel during demineralization, measured by OCT, could be related to the amount of mineral lost during the demineralization process. (C) 2003 Society of Photo-Optical Instrumentation Engineers.