Clinical observation of the efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema.
Clinical observation of the efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema.
复制标题
贝伐珠单抗联合氩绿激光治疗眼底黄斑水肿的临床观察
DOI：
10.3892/etm.2017.4145
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发表时间：
2017-04
影响因子：
2.7
通讯作者：
Gao GP
中科院分区：
文献类型：
--
作者：
Shao Y;Yu Y;Li C;Pei CG;Tu P;Han Y;Gao GP
目的探讨贝伐单抗联合氩绿色激光治疗眼底黄斑水肿的临床疗效。2009年5月至2013年4月，78例在南昌大学第一附属医院寻求治疗的黄斑水肿患者入组本研究。将患者随机分为两组：i）实验组（n=39）和对照组（n=39）。实验组采用贝伐单抗（Avastin®）联合氩绿色激光治疗，对照组仅采用氩绿色激光治疗。比较两种治疗方法的疗效及术后不良反应。结果显示，两组治疗后黄斑中心凹厚度均明显降低，但联合治疗的疗效更为显著。实验组患者在治疗1个月后获得最佳矫正视力，对照组患者在治疗3个月后获得最佳矫正视力。我们得出结论，安维汀®与氩绿色激光联合使用安全有效。视力明显提高，不良反应少。
We studied the clinical efficacy of Bevacizumab combined with argon green laser in treating fundus macular edema. From May 2009 to April 2013, 78 patients seeking treatment for macular edema in the First Affiliated Hospital of Nanchang University were enrolled in this study. Patients were randomly divided into two groups: i) The experimental group (n=39) and the control group (n=39). Patients in the experimental group were treated with Bevacizumab (Avastin®) combined with argon green laser, and those in the control group were treated exclusively with argon green laser. Therapeutic effects were compared, and postoperative adverse reactions caused by both treatment methods were compared. Our results showed that, after treatment, the macular foveal thickness was reduced noticeably in both groups, while the therapeutic effect of combined treatment was more prominent. Patients in the experimental group gained the best-corrected visual acuity after one month of treatment, while patients in the control group achieved that after three months of treatment. We concluded that the use of Avastin® combined with argon green laser was safe and effective. Visual acuity was improved obviously with minimum adverse reactions.