Alcohol abuse and dependence criteria as predictors of a chronic course of alcohol use disorders in the general population
Alcohol abuse and dependence criteria as predictors of a chronic course of alcohol use disorders in the general population
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DOI：
10.1093/alcalc/agh183
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发表时间：
2005-09-01
影响因子：
2.8
通讯作者：
Vollebergh, WAM
中科院分区：
文献类型：
--
作者：
De Bruijn, C;Van den Brink, W;Vollebergh, WAM
目的：研究DSM-IV滥用和依赖标准与ICD-10渴求标准在预测一般人群酒精使用障碍（AUD）慢性病程方面的差异。研究方法：数据来自荷兰心理健康调查和发病率研究，这是荷兰一般人群的一个大型代表性样本，有基线和1年和3年的随访评估。在本研究中，对基线时诊断为DSM-IV AUD的受试者队列进行了随访（n = 382）。根据DSM-IV和ICD-10的诊断标准，使用复合国际诊断访谈（CIDI）进行评估。结果如下：在我们基线时诊断为AUD的受试者队列中，除耐受性外，所有依赖性标准的存在均显著增加了1年和3年随访时的依赖性风险。滥用标准在随访时显示出低得多的依赖性风险，并且通常不显著，但“法律的问题”标准除外。在1年（RR = 12.4，95%CI = 5.5-27.8）和3年随访（RR = 12.9，95%CI = 4.4-37.7）时，ICD-10标准“渴望”在所有依赖性标准中具有最高的相对风险（RR）。结论：除耐受性外，所有DSM-IV依赖性标准都有助于预测一般人群的AUD病程。
Aims: To investigate whether DSM-IV abuse and dependence criteria and the ICD-10 criterion for craving differentially predict a chronic course of alcohol use disorders (AUD) in the general population. Methods: Data were derived from the Netherlands Mental Health Survey and Incidence Study, a large representative sample of the general Dutch population with a baseline and a 1- and 3-year follow-up assessment. In the present study, a cohort of subjects with a DSM-IV AUD diagnosis at baseline was followed (n = 382). Diagnostic criteria of AUD according to DSM-IV and ICD-10 were assessed using the Composite International Diagnostic Interview (CIDI). Results: In our cohort of subjects with an AUD diagnosis at baseline, the presence of all dependence criteria, except tolerance, significantly increased the risk for dependence at 1 and 3 years follow-up. Abuse criteria displayed much lower and often non-significant risks for dependence at follow-up, with the exception of the criterion 'legal problems'. The ICD-10 criterion 'craving' had the highest relative risk (RR) of all criteria for dependence at 1 year (RR = 12.4, 95% CI = 5.5-27.8) and 3 years follow-up (RR = 12.9, 95% CI = 4.4-37.7). Conclusion: With the exception of tolerance, all DSM-IV dependence criteria are useful in predicting the course of AUD in the general population.