Evaluation of analgesic effect of skin-to-skin contact compared to oral glucose in preterm neonates
Evaluation of analgesic effect of skin-to-skin contact compared to oral glucose in preterm neonates
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DOI：
10.1016/j.pain.2008.02.031
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发表时间：
2008-09-30
期刊：
影响因子：
7.4
通讯作者：
Lamy, Zeni Carvalho
中科院分区：
文献类型：
--
作者：
de Sousa Freire, Najala Borges;Santos Garcia, Joao Batista;Lamy, Zeni Carvalho
非药物干预是缓解早产儿小手术期间疼痛的重要替代方法。皮肤接触或袋鼠妈妈式护理是照顾低体重早产儿的一种人性化且有效的方式。本研究的目的是评估袋鼠护理与口服葡萄糖相比对健康早产新生儿对低强度急性疼痛刺激的反应的镇痛效果。将 95 名月经后年龄为 28-36 周的早产新生儿以单盲方式随机分为三组。第 1 组（孤立组，n = 33）。在足跟采血期间，新生儿在 isolette 中处于俯卧位，并且没有接受镇痛。第 2 组（袋鼠法，n = 31）。在足跟采血手术之前和过程中，新生儿保持皮肤接触 10 分钟。第 3 组（葡萄糖，n = 31）。新生儿在隔离室中处于俯卧位并接受口服葡萄糖（1 ml，25%）。足跟采血前 2 分钟。心率 (P = 0.0001) 和血氧饱和度 (p = 0.0012) 变化较小，面部活动持续时间较短（眉毛凸出、挤眼和皱鼻唇沟）(p < 0.0001)。第 2 组观察到较低的 PIPP（早产儿疼痛概况）评分 (p = 0.0001)。 结论。皮肤与皮肤接触 在足跟采血期间对早产儿产生镇痛作用。 (C) 2008 年国际疼痛研究协会。由 Elsevier B.V. 出版。保留所有权利。
Nonpharmacological interventions are important alternatives for pain relief during minor procedures in preterm neonates. Skin-to-skin contact or kangaroo mother care is a human and efficient way of caring for low-weight preterm neonates. The aim of the Present Study was to assess the analgesic effect of kangaroo care compared to oral glucose on the response of healthy preterm neonates to a low-intensity acute painful stimulus. Ninety-five preterm neonates with a postmenstrual age of 28-36 weeks were randomly assigned to three groups in a single-blind manner. In group 1 (isolette, n = 33). the neonate was in the prone position in the isolette during heel lancing and did not receive analgesia. In group 2 (kangaroo method, n = 31). the neonate was held in skin-to-skin contact for 10 min before and during the heel-lancing procedure. In group 3 (glucose, n = 31). the neonate was in the prone position in the isolette and received oral glucose (1 ml, 25%). 2 min before heel lancing. A smaller variation in heart rate (P = 0.0001) and oxygen saturation (p = 0.0012), a shorter duration of facial activity (brow bulge. eye squeeze and nasolabial furrowing) (p 0.0001). and a lower PIPP (Premature Infant Pain Profile) score (p = 0.0001) were observed in group 2. In Conclusion. skin-to-skin contact Produced an analgesic effect in preterm newborns during heel lancing. (C) 2008 International Association for the study of Pain. Published by Elsevier B.V. All rights reserved.