Brain Aromatase and Territorial Aggression Across the Seasons in Male Song Sparrows

Brain Aromatase and Territorial Aggression Across the Seasons in Male Song Sparrows
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雄性歌麻雀的大脑芳香酶和跨季节的领地攻击

DOI:
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发表时间:
2012
期刊:
影响因子:
--
通讯作者:
K. Soma
K. Soma
中科院分区:
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文献类型:
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作者:
S. Heimovics;H. B. Fokidis;K. Soma

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雌激素调节多种社会行为,包括欲望和性行为、社会关系和攻击性。我们对雌激素在社会行为中的作用的理解大部分来自对驯养小鼠和大鼠的实验室研究(Blumstein等人,2010;索马等人,2008年)。除了这项工作之外,对自由生活的动物的实地研究提供了一个机会,可以研究雌激素如何在生态相关的背景下调节自然发生的社会行为。这项工作很重要,因为它为复杂社会行为的雌激素调节提供了新的见解和视角,并且对于全面了解雌激素调节社会行为的各种背景至关重要。其中一个例子是研究17 β -雌二醇(E2)在不同季节调节雄性歌雀(Melospiza melodia)领土攻击中的作用。我们对鸣禽的自然历史、行为、社会模式和季节性内分泌生理的了解远远超过大多数脊椎动物。鸣禽麻雀在睾丸激素和攻击性原则的形成中发挥了关键作用,例如Wingfield等人(1990)描述的挑战假说。此外,鸣禽脑比非鸣禽物种(包括啮齿动物)更广泛地且以更高丰度表达雌激素合成酶芳香化酶(Forlano等人,2006年)。此外,鸣禽的行为和成年神经可塑性是高度雌激素敏感的和季节性可变的(Ball等人,2004年;索马,2006年; Schlinger等人,2008年)。总之,这些因素使鸣禽成为研究复杂社会行为的雌激素调节的杰出模型系统。
Estrogens regulate a variety of social behaviors, including appetitive and consummatory sexual behavior, social affi liation, and aggression. Much of our understanding of the roles of estrogens in social behavior comes from laboratory studies of domesticated mice and rats (Blumstein et al., 2010; Soma et al., 2008). In addition to this work, fi eld studies of free-living animals off er the opportunity to investigate how estrogens regulate naturally occurring social behaviors within an ecologically relevant context. Such work is important because it has provided novel insights and perspectives into the estrogenic regulation of complex social behaviors and has been critical to developing a comprehensive understanding of the variety of contexts in which estrogens regulate social behavior. One such example is research on the role of 17 β -estradiol (E 2 ) in regulating male song sparrow ( Melospiza melodia ) territorial aggression in diff erent seasons. Our understanding of songbird natural history, behavior, social patterning, and seasonal endocrine physiology is far greater than for most vertebrates. Song sparrows played a critical role in the formulation of principles about testosterone and aggression, such as the Challenge Hypothesis described by Wingfi eld et al. (1990). Further, the songbird brain expresses the estrogen-synthetic enzyme aromatase more widely and in higher abundance than nonsongbird species, including rodents (Forlano et al., 2006). Moreover, songbird behavior and adult neuroplasticity are highly estrogen sensitive and seasonally variable (Ball et al., 2004; Soma, 2006; Schlinger et al., 2008). Together, these factors make songbirds outstanding model systems for studying estrogenic regulation of complex social behaviors.
野生雄性歌麻雀的脑芳香酶、5α-还原酶和 5β-还原酶随季节变化:与攻击性和性行为的关系。
DOI: 10.1002/neu.10225
发表时间: 2003
期刊: Journal of neurobiology
影响因子: --
作者:
Soma,KiranK;Schlinger,BarneyA;Wingfield,JohnC;Saldanha,ColinJ
通讯作者: Saldanha,ColinJ
雄性鸣禽体内循环的雌激素源自大脑。
DOI: 10.1073/pnas.89.16.7650
发表时间: 1992
影响因子: 11.1
作者:
Schlinger,BA;Arnold,AP
通讯作者: Arnold,AP
DOI: --
发表时间: 2008
影响因子: 4.2
作者:
B. Schlinger;D. S. Pradhan;K. Soma
通讯作者: B. Schlinger;D. S. Pradhan;K. Soma
Fadrozole:斑胸草雀大脑中芳香酶的一种有效且特异性的抑制剂。
DOI: 10.1006/gcen.1994.1059
发表时间: 1994
影响因子: 2.7
作者:
Wade,J;Schlinger,BA;Hodges,L;Arnold,AP
通讯作者: Arnold,AP
DOI: 10.1002/neu.10288
发表时间: 2004-02-15
期刊: JOURNAL OF NEUROBIOLOGY
影响因子: --
作者:
Soma, KK;Tramontin, AD;Brenowitz, EA
通讯作者: Brenowitz, EA