Stealthy microbes: How Neisseria gonorrhoeae hijacks bulwarked iron during infection.
Stealthy microbes: How Neisseria gonorrhoeae hijacks bulwarked iron during infection.
复制标题
隐形微生物：淋病奈瑟菌如何在感染过程中劫持坚固的铁。
DOI：
10.3389/fcimb.2022.1017348
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发表时间：
2022
影响因子：
5.7
通讯作者：
中科院分区：
文献类型：
--
作者：
Transition metals are essential for metalloprotein function among all domains of life. Humans utilize nutritional immunity to limit bacterial infections, employing metalloproteins such as hemoglobin, transferrin, and lactoferrin across a variety of physiological niches to sequester iron from invading bacteria. Consequently, some bacteria have evolved mechanisms to pirate the sequestered metals and thrive in these metal-restricted environments. Neisseria gonorrhoeae, the causative agent of the sexually transmitted infection gonorrhea, causes devastating disease worldwide and is an example of a bacterium capable of circumventing human nutritional immunity. Via production of specific outer-membrane metallotransporters, N. gonorrhoeae is capable of extracting iron directly from human innate immunity metalloproteins. This review focuses on the function and expression of each metalloprotein at gonococcal infection sites, as well as what is known about how the gonococcus accesses bound iron.
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影响因子：
11.2
作者：
Chakraborty, Subhankar;Kaur, Sukhwinder;Guha, Sushovan;Batra, Surinder K.
通讯作者：
Batra, Surinder K.
影响因子：
3.6
作者：
Belkacem, Anna;Caumes, Eric;Patey, Olivier
通讯作者：
Patey, Olivier
影响因子：
3.2
作者：
Bonnah, RA;Schryvers, AB
通讯作者：
Schryvers, AB
影响因子：
14.8
作者：
Bao G;Clifton M;Hoette TM;Mori K;Deng SX;Qiu A;Viltard M;Williams D;Paragas N;Leete T;Kulkarni R;Li X;Lee B;Kalandadze A;Ratner AJ;Pizarro JC;Schmidt-Ott KM;Landry DW;Raymond KN;Strong RK;Barasch J
通讯作者：
Barasch J
影响因子：
6.4
作者：
Anderson, JE;Leone, PA;Sparling, PF
通讯作者：
Sparling, PF