Virologic Response to Early Antiretroviral Therapy in HIV-infected Infants: Evaluation After 2 Years of Treatment in the Pediacam Study, Cameroon
Virologic Response to Early Antiretroviral Therapy in HIV-infected Infants: Evaluation After 2 Years of Treatment in the Pediacam Study, Cameroon
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DOI：
10.1097/inf.0000000000001745
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发表时间：
2018-01-01
影响因子：
3.6
通讯作者：
Warszawski, Josiane
中科院分区：
文献类型：
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作者：
Ndongo, Francis Ateba;Texier, Gaetan;Warszawski, Josiane
在资源有限的环境中，对艾滋病毒感染婴儿早期抗逆转录病毒治疗（ART）的病毒学反应知之甚少。我们估计了在开始抗逆转录病毒治疗2年内实现病毒抑制的可能性，并调查了与成功相关的因素。方法：我们分析了来自喀麦隆Pediacam的所有190名在12个月前开始抗逆转录病毒治疗的婴儿。主要结局指标为病毒抑制(
Introduction: Little is known about virologic responses to early antiretroviral therapy (ART) in HIV-infected infants in resource-limited settings. We estimated the probability of achieving viral suppression within 2 years of ART initiation and investigated the factors associated with success.Methods: We analyzed all 190 infants from the Cameroon Pediacam who initiated ART by 12 months of age. The main outcome measure was viral suppression (