Acute Hemolysis with Renal Failure due to Clostridium Bacteremia in a Patient with AML
Acute Hemolysis with Renal Failure due to Clostridium Bacteremia in a Patient with AML
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DOI：
10.1155/2016/6549268
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发表时间：
2016-01-01
影响因子：
1.1
通讯作者：
Nugent, K.
中科院分区：
文献类型：
--
作者：
Medrano-Juarez, R. M.;Sotello, D.;Nugent, K.
我们提出一例急性溶血性贫血，肾功能衰竭，并产气荚膜梭菌菌血症的病人急性髓性白血病。产气荚膜梭菌血症的高致死率要求临床医生识别并迅速治疗有感染风险的患者。虽然其他溶血过程也可用于这些事件的鉴别诊断，但高热、寒战和快速阳性血培养可能有助于缩小诊断范围。大多数产气荚膜梭菌菌血症病例伴有合并感染，这使得广谱经验性治疗必不可少。与白血病相关的产气荚膜梭菌感染死亡率很高。
We present a case of acute hemolytic anemia, renal failure, and Clostridium perfringens bacteremia in a patient with acute myelogenous leukemia. The high fatality of C. perfringens bacteremia requires that clinicians recognize and rapidly treat patients at risk for this infection. Although other hemolytic processes are in the differential diagnosis of these events, the presence of high fever, chills, and rapidly positive blood cultures may help narrow the diagnosis. Most cases of C. perfringens bacteremia have a concomitant coinfection, which makes broad spectrum empiric therapy essential. There is a high mortality rate of C. perfringens infections associated with leukemia.