Structure and Distribution of Glycoproteins and Glycosaminoglycans
Structure and Distribution of Glycoproteins and Glycosaminoglycans
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糖蛋白和糖胺聚糖的结构和分布
DOI：
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发表时间：
1979
期刊：
影响因子：
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通讯作者：
R. U. Margolis
中科院分区：
文献类型：
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作者：
R. Margolis;R. U. Margolis
糖胺聚糖（在旧的命名法中称为粘多糖）是高分子量线性碳水化合物聚合物，通常由糖醛酸（D-葡糖醛酸或L-艾杜糖醛酸）和己糖胺（N-乙酰葡糖胺或N-乙酰半乳糖胺）的二糖重复单元组成。在硫酸化糖胺聚糖的情况下，多糖链在其还原末端通过特征性β-葡糖醛酸基-半乳糖基-半乳糖基-木糖基-丝氨酸序列与蛋白质部分O-糖苷连接。
The glycosaminoglycans (called mucopolysaccharides in the older nomenclature) are high-molecular-weight linear carbohydrate polymers that are generally composed of disaccharide repeating units of a uronic acid (D-gluc- uronic acid or L-iduronic acid) and a hexosamine (N-acetylglucosamine or N-acetylgalactosamine). In the case of the sulfated glycosaminoglycans, the polysaccharide chains are O-glycosidically linked at their reducing ends to a protein moiety through the characteristic -glucuronosyl-galactosyl- galactosyl-xylosyl-serine sequence.