Post-COVID-19 inflammatory syndrome manifesting as refractory status epilepticus
Post-COVID-19 inflammatory syndrome manifesting as refractory status epilepticus
复制标题
DOI：
10.1111/epi.16683
复制
发表时间：
2020-09-18
期刊：
影响因子：
5.6
通讯作者：
Lewis, Ariane
中科院分区：
文献类型：
--
作者：
Carroll, Elizabeth;Neumann, Henry;Lewis, Ariane
在COVID-19患者的急性感染期，有多种癫痫发作的描述。然而，尚未有COVID-19感染康复后癫痫持续状态的报告。在此，我们讨论一例在首次感染COVID-19后6周出现难治性癫痫持续状态的患者。广泛的检查显示炎症标志物升高，鼻咽SARS-CoV-2聚合酶链反应阳性复发，海马萎缩。感染后炎症可能以类似于COVID-19后在儿童中观察到的多系统炎症综合征的方式触发了难治性癫痫持续状态。
There have been multiple descriptions of seizures during the acute infectious period in patients with COVID-19. However, there have been no reports of status epilepticus after recovery from COVID-19 infection. Herein, we discuss a patient with refractory status epilepticus 6 weeks after initial infection with COVID-19. Extensive workup demonstrated elevated inflammatory markers, recurrence of a positive nasopharyngeal SARS-CoV-2 polymerase chain reaction, and hippocampal atrophy. Postinfectious inflammation may have triggered refractory status epilepticus in a manner similar to the multisystemic inflammatory syndrome observed in children after COVID-19.