Yeast prions and evolvability

Yeast prions and evolvability
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DOI:
10.1016/s0168-9525(01)02235-1
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发表时间:
2001-04-01
期刊:
影响因子:
11.4
通讯作者:
Pál, C
Pál, C
中科院分区:
生物学1区
文献类型:
--
作者:
Pál, C

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虽然遗传和遗传变异的许多奥秘已经被孟德尔遗传学和现代合成所解开,但是否有任何有助于进化过程的遗传特征仍然不清楚。新的研究表明,酵母蛋白在不利条件下提供了一种选择性优势,可能是通过产生表型变异。这是否也意味着Prion决定簇被保留是因为它有助于进化?
Although much of the mystery of heredity and genetic variation has been dispelled by mendelian genetics and the modern synthesis, it is still unclear whether there are any genetic traits for facilitating the process of evolution. New work reveals that a yeast prion provides a selective advantage under adverse conditions, possibly by producing phenotypic variants. Does it also imply that the prion determinant is retained because it aids evolution?.