Magnetic resonance imaging findings in sudden sensorineural hearing loss
Magnetic resonance imaging findings in sudden sensorineural hearing loss
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DOI：
10.2310/7070.2006.0066
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发表时间：
2006-10-01
期刊：
影响因子：
--
通讯作者：
Colosimo, Cesare
中科院分区：
文献类型：
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作者：
Cadoni, Gabriella;Cianfoni, Alessandro;Colosimo, Cesare
目的：目的：探讨磁共振成像（MRI）在突发感音神经性聋（SSNHL）诊断中的作用。使用八通道相控阵头部线圈进行MRI，以研究整个听前庭通路和整个大脑。方案研究包括颞骨、内耳道（IAC）、桥小脑角（CPA）和脑干的高分辨率研究，结合2 mm薄层轴向T-2加权二维快速自旋回波（FSE）和液体衰减反转恢复（FLAIR）序列，对比前后（钆-二亚乙基三胺五乙酸）给药脂肪抑制轴向T-1加权二维FSE序列，和T-2* 加权三维傅立叶变换-稳态序列相长干涉（FT-CISS），具有0.4mm的间隔。结果：54例SSNHL中31例（57%）表现为MRI异常。在54例病例中，6例检出的异常与临床表现直接相关（2例脑干出血，1例耳蜗炎症，1例听神经瘤，1例CPA蛛网膜囊肿，1例脑桥白色物质病变，与沿着中枢听前庭神经通路的脱髓鞘斑块相一致，是多发性硬化的首次表现）。建议在顺磁造影剂给药前后对听前庭神经通路和全脑进行广泛的MRI研究，以排除可能导致SSNHL的广泛异常。
Objective: To investigate the role of magnetic resonance imaging (MRI) in the diagnosis of sudden sensorineural hearing loss (SSNHL).Methods: Fifty-four consecutive patients affected by SSNHL were investigated using brain MRI. MRI was performed with an eight-channel phased-array head coil to study the entire audiovestibular pathway and the whole brain. The protocol study consisted of a high-resolution study of the temporal bone, internal auditory canal (IAC), cerebellopontine angle (CPA), and brainstem combining 2 mm thin-slice axial T-2-weighted two-dimensional fast spin echo (FSE) and fluid-attenuated inversion recovery (FLAIR) sequences, pre- and postcontrast (gadolinium-diethylenetriamine pentaacetic acid) administration fat-suppressed axial T-1-weighted two-dimensional FSE sequences, and a T-2*-weighted three-dimensional Fourier transformation-constructive interference in steady state sequence (FT-CISS), with 0.4 mm ultrathin partitions. The rest of the brain was studied with a 4 mm axial T2-weighted FLAIR sequence.Results: Thirty-one of 54 (57%) cases of SSNHL presented with MRI abnormalities. In 6 of 54 cases, the detected abnormality was directly correlated to the clinical picture (2 labyrinthine hemorrhage, 1 cochlear inflammation, 1 acoustic neuroma, 1 arachnoid cyst of the CPA, and 1 case of white matter lesions in the pons, compatible with demyelinating plaques along the central audiovestibular nervous pathway, as the first expression of multiple sclerosis).Conclusions: An extensive MRI study of the audiovestibular nervous pathway and of the whole brain, pre- and postparamagnetic contrast administration, is recommended to rule out the wide spectrum of abnormalities that can cause SSNHL.