Methods for minimizing the loss of genetic diversity in conserved populations with overlapping generations
Methods for minimizing the loss of genetic diversity in conserved populations with overlapping generations
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DOI：
10.1007/s10592-005-9025-5
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发表时间：
2005-12
影响因子：
2.2
通讯作者：
T. Nomura
中科院分区：
文献类型：
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作者：
T. Nomura
理论上证明，种群中平均祖先的最小化是保护遗传多样性的最有效方法。在本研究中，基于群体遗传模型，开发了两种最小化重叠代群体中平均血统的方法。对于给定的亲代共性结构，第一种方法（OG）最小化下一代的平均共性，第二种方法（LT）旨在最小化长期积累的共性。通过随机模拟检验了两种方法的效率。与随机选择父母相比，两种方法下的年有效种群规模增加了 2-3 倍。在世代间隔短的群体中，两种方法之间的差异很小。对于世代间隔较长的种群，OG方法显示最初几年的年有效规模略大。然而，在随后的几年中，LT 方法的年有效规模比 OG 方法大 5-15%。从这些结果来看，在大多数实际情况下，LT 方法优于 OG 方法。
Minimization of the average coancestry in a population has been theoretically proven to be the most efficient method to preserve genetic diversity. In the present study, based on a population genetic model, two methods to minimize the average coancestry in populations with overlapping generations were developed. For a given parental coancestry structure, the first method (OG) minimizes the average coancestry in the next generation, and the second method (LT) is designed to minimize the long-term accumulation of coancestry. The efficiencies of the two methods were examined by stochastic simulation. Compared to random choice of parents, the annual effective population sizes under the two proposed methods increased 2–3 folds. The difference among the two methods was small in a population with short generation interval. For populations with long generation intervals, the OG method showed a slightly larger annual effective size in an initial few years. However, in the subsequent years, the LT method gave a 5–15% larger annual effective size than the OG method. From these results, it is suggested that the LT method would be preferred to the OG method in most practical situations.