NASAL POLYPS IN ASTHMA AND RHINITIS - REVIEW OF 6,037 PATIENTS

NASAL POLYPS IN ASTHMA AND RHINITIS - REVIEW OF 6,037 PATIENTS
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DOI:
10.1016/0091-6749(77)90171-3
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发表时间:
1977-01-01
影响因子:
14.2
通讯作者:
CHAFEE, FH
CHAFEE, FH
中科院分区:
医学1区
文献类型:
--
作者:
SETTIPANE, GA;CHAFEE, FH

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我们回顾了罗得岛医院成人过敏门诊和成人过敏私人诊所的哮喘和鼻炎患者的记录数据。在4986名总人群中,鼻息肉的发生率为4.2%;在哮喘部分人群中,鼻息肉的发生率为6.7%,在单纯鼻炎组中,鼻息肉的发生率为2.2%。吸入性过敏原皮试阴性的哮喘患者鼻息肉发生率明显高于皮试阳性的哮喘患者,分别为12.5%和5.0%(P < 0.01)。鼻息肉的发病率随年龄的增长而增加。在211例鼻息肉患者中,7例合并哮喘,29%合并鼻炎。此外,14%的鼻息肉患者有阿司匹林不耐受,主要是支气管痉挛型。此外,1051例平均年龄为6岁的哮喘和鼻炎患者从儿科过敏门诊进行了类似的评价。这些儿科患者中只有1例(0.1%)患有鼻息肉。
Data from records of patients with asthma and rhinitis in the Rhode Island [USA] Hospital Adult Allergy Clinic and in an adult allergy private practice were reviewed. The frequency of nasal polyps in the total population of 4986 was 4.2%; in the asthmatic portion the population the frequency was 6.7% and in the rhinitis alone group the frequency was 2.2%. Asthmatics with negative allergy skin tests to inhalant allergers had significantly more nasal polyps than asthmatics with positive skin tests, 12.5% vs. 5.0% P < 0.01. The frequency of nasal polyps increased with advancing years. Of the total 211 cases of nasal polyps, 7 had asthma and 29% had rhinitis alone. Also, 14% of the patients with nasal polyps had aspirin intolerance, primarily of the bronchospastic type. In addition, 1051 patients with asthma and rhinitis from the Pediatric Allergy Clinic with a mean age of 6 yr were similarly evaluated. Only 1 (0.1%) of these pediatric patients had nasal polyps.