Scutellarein attenuates atopic dermatitis by selectively inhibiting transient receptor potential vanilloid 3 channels
Scutellarein attenuates atopic dermatitis by selectively inhibiting transient receptor potential vanilloid 3 channels
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DOI:
10.1111/bph.15913
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发表时间:
2022-06
影响因子:
7.3
通讯作者:
Yujing Wang;Liaoxi Tan;Kejun Jiao;Chu Xue;Qinglian Tang;Shan Jiang;Younan Ren;Hao Chen;T. El-Aziz;Khalid N. M. Abdelazeem;Ye Yu;Fang Zhao;M. Zhu;Zhengyu Cao
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文献类型:
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作者:
Yujing Wang;Liaoxi Tan;Kejun Jiao;Chu Xue;Qinglian Tang;Shan Jiang;Younan Ren;Hao Chen;T. El-Aziz;Khalid N. M. Abdelazeem;Ye Yu;Fang Zhao;M. Zhu;Zhengyu Cao
Atopic dermatitis (AD) is one of the most common chronic inflammatory cutaneous diseases with unmet clinical needs. As a common ingredient found in several medicinal herbs with efficacy on cutaneous inflammatory diseases, Scutellarein (Scu) has been shown to possess anti‐inflammatory and anti‐proliferative activities. We aimed to evaluate the therapeutic efficacy of Scu against AD and its underlying molecular mechanism.