Fatigue, tiredness, and lack of energy improve with treatment for OSA.
Fatigue, tiredness, and lack of energy improve with treatment for OSA.
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DOI：
10.5664/jcsm.27490
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发表时间：
2009-06
期刊：
影响因子：
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通讯作者：
Wattanachai Chotinaiwattarakul;L. O’Brien;L. Fan;R. Chervin
中科院分区：
文献类型：
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作者：
Wattanachai Chotinaiwattarakul;L. O’Brien;L. Fan;R. Chervin
许多阻塞性睡眠呼吸暂停患者抱怨疲劳，疲倦，或缺乏能量，除了嗜睡，或代替嗜睡。我们探讨了自我定义的疲劳、疲倦和缺乏能量是否在气道正压通气（PAP）治疗后得到改善，如嗜睡。方法：我们对一所大学睡眠障碍中心的成年人进行了一项前瞻性调查，并通过多导睡眠图证实患有阻塞性睡眠呼吸暂停。调查邮寄给1539名患者6个月至3年后，他们规定PAP家庭使用。结果参与者（n = 313）包括183名报告每晚使用PAP ≥ 5小时的患者，96名因没有积极治疗或每晚使用PAP < 5小时而被认为治疗不充分的患者，34名通过手术或其他方式治疗，因此被排除在后续分析之外。与基线相比，在随访时，坚持PAP的受试者报告的疲劳、疲倦、缺乏能量和嗜睡减少（每种p < 0.05）。除缺乏能量外，坚持PAP的受试者的每种症状的改善均显著优于治疗不充分的受试者（p < 0.05）。结论：患者主诉疲劳、疲倦和缺乏精力，如嗜睡，可通过对PAP治疗阻塞性睡眠呼吸暂停的良好依从性得到显著改善。因此，那些喜欢用一系列常见的、相关的术语（而不是嗜睡）来描述他们的问题的患者可能会从任何潜在的睡眠呼吸障碍的调查和治疗中受益。
OBJECTIVES Many patients with obstructive sleep apnea complain of fatigue, tiredness, or lack of energy in addition to sleepiness, or instead of sleepiness. We explored whether self-defined fatigue, tiredness, and lack of energy improve, like sleepiness, after treatment with positive airway pressure (PAP). METHODS We conducted a prospective survey of adults referred to a University-based sleep disorders center and confirmed to have obstructive sleep apnea on polysomnography. Surveys were mailed to 1539 patients 6 months to 3 years after they were prescribed PAP for home use. RESULTS Participants (n = 313) included 183 who reported using PAP > or = 5 hours per night, 96 who were considered inadequately treated because they had no active treatment or used PAP < 5 hours per night, and 34 treated by surgery or other means and therefore excluded from subsequent analysis. At follow-up in comparison to baseline, subjects adherent to PAP reported less fatigue, tiredness, lack of energy, and sleepiness (p < 0.05 for each). Improvement of each symptom except for lack of energy was significantly better (p < 0.05) among PAP-adherent subjects than among inadequately treated subjects. CONCLUSIONS Patients' complaints of fatigue, tiredness, and lack of energy, like sleepiness, can improve substantially with good adherence to PAP for obstructive sleep apnea. Therefore, patients who prefer a range of common, related terms other than sleepiness to describe their problem may benefit from investigation and treatment for any underlying sleep-disordered breathing.