Facile incorporation of aggregation-induced emission materials into mesoporous silica nanoparticles for intracellular imaging and cancer therapy.
Facile incorporation of aggregation-induced emission materials into mesoporous silica nanoparticles for intracellular imaging and cancer therapy.
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DOI：
10.1021/am302512u
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发表时间：
2013-03
影响因子：
9.5
通讯作者：
Xiaoyong Zhang;Xiqi Zhang;Shiqi Wang;Meiying Liu;Yun Zhang;Lei Tao;Yen Wei
中科院分区：
文献类型：
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作者：
Xiaoyong Zhang;Xiqi Zhang;Shiqi Wang;Meiying Liu;Yun Zhang;Lei Tao;Yen Wei
采用一锅法表面活性剂模板法制备了介孔二氧化硅纳米颗粒(MSN)中的聚集诱导发射(AIE)材料。进一步探索了这种荧光MSN在细胞成像和癌症治疗中的应用。我们证明了AIE-MSN纳米复合材料具有很强的荧光和均匀的形貌，使其在细胞成像和癌症治疗方面具有很好的应用前景。
Aggregation-induced emission (AIE) materials were facilely incorporated into mesoporous silica nanoparticles (MSNs) via one-pot surfactant templated method. Cell imaging and cancer therapy applications of such fluorescent MSNs were further explored. We demonstrated that AIE-MSN nanocomposites showed strong fluorescence and uniform morphology, making them promising for both cell imaging and cancer therapy.