Four-dimensional measurement of lung tumor displacement using 256-multi-slice CT-scanner
Four-dimensional measurement of lung tumor displacement using 256-multi-slice CT-scanner
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DOI：
10.1016/j.lungcan.2006.11.011
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发表时间：
2007-04-01
期刊：
影响因子：
5.3
通讯作者：
Baba, Masayuki
中科院分区：
文献类型：
--
作者：
Mori, Shinichiro;Endo, Masahiro;Baba, Masayuki
内靶体积的概念对于肺肿瘤的放射治疗具有显著的重要性，因为呼吸诱导的运动是重要的。需要对运动进行个体化评估，因为肿瘤部位可能无法预测肿瘤运动的程度或模式。我们使用256层多层螺旋CT（256MSCT）进行容积电影扫描，研究14例接受碳离子放射治疗的住院患者在自由呼吸时肿瘤的运动。电影CT的16个呼吸时相的运动评估显示，大多数肿瘤显示出类似呼吸道的行为。右肺和左肺平均呼气峰值和吸气峰值之间的等中心位移，上叶、中叶和塔叶分别为7 mm、7 mm和15 mm。256MSCT电影CT改善了肿瘤移位的评价，克服了当前CT方法的一些局限性。容积电影CT数据为肺部肿瘤的所有放射方法的计划提供了有用的运动数据。(c)2006爱思唯尔爱尔兰有限公司保留所有权利。
The concept of internal target volume is of marked importance for radiotherapy to lung tumors as respiration-induced motion is important. Individualized assessment of motion is required as tumor site may not predict the extent or pattern of tumor motion. We performed volumetric cine scanning using the 256-multi-slice CT (256MSCT) to study tumor motion during free breathing in 14 inpatients who were treated with carbon-ion radiotherapy. Motion assessment in 16 respiratory phases of the cine CT revealed most tumors to show hysteresis-like behavior. Isocenter displacement between peak exhalation and inhalation for the average of the right and left lungs were 7 mm, 7 mm and 15 mm for the upper, middle and tower lobes, respectively. Cine CT with the 256MSCT improved the evaluation of tumor displacement and overcomes some of the limitations associated with current CT methods. Volumetric cine CT data provides useful data on motion for planning in all radiation approaches for Lung tumors. (c) 2006 Elsevier Ireland Ltd. All rights reserved.