The role of the amygdala and rostral anterior cingulate in encoding expected outcomes during learning
The role of the amygdala and rostral anterior cingulate in encoding expected outcomes during learning
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DOI：
10.1016/j.neuroimage.2005.07.060
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发表时间：
2006-02-15
期刊：
影响因子：
5.7
通讯作者：
Blair, RJR
中科院分区：
文献类型：
--
作者：
Kosson, DS;Budhani, S;Blair, RJR
成功的被动回避学习被认为需要使用习得的刺激-强化关联来指导决策[Baxter， m.g., Murray, e.a., 2002]。杏仁核和奖励。自然评论。神经科学[j]。本实验研究了19名健康成人成功被动回避学习的神经相关因素。在行为上，受试者表现出一种独特的表现模式：早期对刺激的不加区分的反应（标准前的表现），随后是相对快速的学习，然后是成功表现的平台期（标准后的表现）。比较标准后正确反应的神经反应和标准前正确反应的神经反应。标准后的正确反应与扣带吻侧前部、脑岛、尾状核、海马区和杏仁核等区域的激活增加有关。Elsevier Inc.出版。
Successful passive avoidance learning is thought to require the use of learned stimulus-reinforcement associations to guide decision making [Baxter, M.G., Murray, E.A., 2002. The amygdala and reward. Nature Reviews. Neuroscience 3, 563-573]. The current experiment investigated the neural correlates of successful passive avoidance learning in 19 healthy adults. Behaviorally, subjects showed a distinct pattern of performance: early indiscriminate responding to stimuli (pre-criterion performance), followed by relatively rapid learning before a plateau of successful performance (post-criterion performance). Neural responses to post-criterion correct responses were compared with neural responses to both incorrect responses and pre-criterion correct responses. Post-criterion correct responding was associated with increased activation in regions including rostral anterior cingulate, insula, caudate, hippocampal regions, and the amygdala. Published by Elsevier Inc.