Head injury and brain ischaemia--implications for therapy.
Head injury and brain ischaemia--implications for therapy.
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头部损伤和脑缺血——对治疗的影响。
DOI：
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发表时间：
1985
影响因子：
9.8
通讯作者：
J. Miller
中科院分区：
文献类型：
--
作者：
J. Miller
脑缺血是脑损伤后常见且重要的后遗症。在持续严重头部损伤（即与昏迷相关的损伤）的患者中，尸检时几乎不变地发现缺血性脑损伤区域（Graham，亚当斯和Doyle，1978）。严重头部损伤的残疾幸存者的头部的连续计算机断层扫描经常显示相当大的脑梗塞（米勒等人，1980年）。创伤性脑撕裂伤也会导致分离血管区域的局部缺血。大脑内侧颞叶通过小脑幕裂孔疝出和脑干轴向下移导致脑动脉供血的拉伸和扭曲，导致脑干和枕叶缺血和梗死（米勒和亚当斯，1984）。因此，脑缺血可能是严重脑损伤后继发性脑功能障碍和损伤的最重要机制。
Brain ischaemia is a frequent and important sequel to brain injury. Areas of ischaemic brain damage are an almost invariable finding at postmortem in patients who have sustained severe head injury— that is, injury associated with coma (Graham, Adams and Doyle, 1978). Sequential computerized tomography of the head in disabled survivors of severe head injury frequently reveals sizeable cerebral infarcts (Miller et al., 1980). Traumatic brain laceration results also in ischaemia in the territory of divided vessels. Herniation of the medial temporal lobe of the brain through the tentorial hiatus and downward axial shift of the brain stem produce stretching and distortion of the brain arterial supply with ischaemia and infarction in the brain stem and occipital lobes (Miller and Adams, 1984). Brain ischaemia may therefore be the single most important mechanism in the production of secondary brain dysfunction and damage after severe head injury.
脑实验性流体冲击损伤对缺氧和高碳酸血症脑血管反应性的影响。
影响因子：
4.1
作者：
Lewelt,W;Jenkins,LW;Miller,JD
通讯作者：
Miller,JD