The causative organisms of septicaemia and their epidemiology.
The causative organisms of septicaemia and their epidemiology.
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DOI：
10.1093/jac/25.suppl_c.41
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Susannah J. Eykyn;W. Gransden;Ian Phillips
中科院分区：
文献类型：
--
作者：
Susannah J. Eykyn;W. Gransden;Ian Phillips
在1969年至1988年的20年间，在圣托马斯医院对近4000例败血症进行了前瞻性研究。40%是社区获得性，60%是医院获得性。总体而言，最常见的分离株是大肠埃希菌（22%）。在社区获得性菌血症，埃施。大肠埃希菌、肺炎链球菌和金黄色葡萄球菌占近60%的发病率，最常见的感染病灶是泌尿道（埃施.大肠杆菌）和呼吸道（肺炎链球菌）。埃施。大肠杆菌在糖尿病患者中特别常见，肺炎链球菌在酗酒者中特别常见。在医院获得性败血症，埃施。大肠杆菌和葡萄球菌。金黄色葡萄球菌占40%，但另外30%是由埃施以外的肠杆菌引起的。大肠杆菌和铜绿假单胞菌。最常见的感染病灶是尿路，通常与导管插入术或仪器，和血管内的访问网站，其中败血症的发作越来越多地引起凝固酶阴性葡萄球菌。
During the 20 years, 1969-88, nearly 4000 episodes of septicaemia were studied prospectively at St. Thomas' Hospital. Forty percent were community-acquired and 60% hospital-acquired. Overall the commonest isolate was Escherichia coli (22%). In community-acquired bacteraemias, Esch. coli, Streptococcus pneumoniae and Staphylococcus aureus accounted for almost 60% of episodes, and the commonest foci of infection were the urinary tract (Esch. coli) and the respiratory tract (Str. pneumoniae). Esch. coli was particularly common in diabetic patients and Str. pneumoniae in alcoholics. In hospital-acquired septicaemia, Esch. coli and Staph. aureus accounted for 40% of episodes, but a further 30% were caused by enterobacteria other than Esch. coli, and Pseudomonas aeruginosa. The commonest foci of infection were the urinary tract, often with catheterization or instrumentation, and intravascular access sites, from which episodes of septicaemia were increasingly caused by coagulase-negative staphylococci.