Jumihaidokuto (Shi-Wei-Ba-Du-Tang), a Kampo Formula, Decreases the Disease Activity of Palmoplantar Pustulosis.
Jumihaidokuto (Shi-Wei-Ba-Du-Tang), a Kampo Formula, Decreases the Disease Activity of Palmoplantar Pustulosis.
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DOI：
10.1155/2016/4060673
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发表时间：
2016
影响因子：
1.5
通讯作者：
Shimizu T
中科院分区：
文献类型：
--
作者：
Mizawa M;Makino T;Inami C;Shimizu T
掌跖脓疱病（PPP）是一种慢性皮肤病，其特征是表皮内无菌脓疱，并伴有手掌和脚底的红斑性鳞屑。Jumihaidokuto是一种由十种药用植物组成的传统草药，在日本被用于治疗化脓性皮肤病。本研究探讨了聚米海多通对PPP患者疾病活动性的影响（n = 10）。PPP患者在服用处方药物的基础上，连续4 - 8周服用聚米海多藤（EKT-6，每天6.0 g）。结果显示，给药后掌足底脓疱性银屑病面积及严重程度指数（PPPASI）明显降低（p < 0.05）。因此，Jumihaidokuto似乎对PPP有效。
Palmoplantar pustulosis (PPP) is a chronic skin disease characterized by sterile intraepidermal pustules associated with erythematous scaling on the palms and soles. Jumihaidokuto is a traditional herbal medicine composed of ten medical plants and has been given to patients with suppurative skin disease in Japan. This study investigated the effect of jumihaidokuto on the disease activity in PPP patients (n = 10). PPP patients were given jumihaidokuto (EKT-6; 6.0 g per day) for 4 to 8 weeks in addition to their prescribed medications. The results showed that the palmoplantar pustular psoriasis area and severity index (PPPASI) was decreased after the administration of jumihaidokuto (p < 0.05). Therefore, Jumihaidokuto is seemingly effective against PPP.