Inhibited Ru(bpy)3 2+ electrochemiluminescence related to electrochemical oxidation activity of inhibitors.
Inhibited Ru(bpy)3 2+ electrochemiluminescence related to electrochemical oxidation activity of inhibitors.
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DOI：
10.1021/ac0702443
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发表时间：
2007-05
影响因子：
7.4
通讯作者：
Yuwu Chi;Yongqiang Dong;Guonan Chen
中科院分区：
文献类型：
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作者：
Yuwu Chi;Yongqiang Dong;Guonan Chen
电化学发光（ECL）作为一种检测无机和有机化合物的有力工具，已被分析化学家所接受。Ru（bpy）32+是最常用的电化学发光体系，人们对Ru（bpy）32+电化学发光体系的增强或抑制作用进行了大量的研究。然而，对该体系的理论研究，特别是对Ru（bpy）32+电化学发光体系的缓蚀机理的研究还不多。在本研究中，发现许多具有电化学氧化活性的无机和有机化合物对Ru（bpy）32+的电化学发光有很强的抑制作用。通过建立相应的模型，提出了一种新的“电化学氧化抑制”机理来解释这些被抑制的ECL现象。通过实验验证了外加电位、非补偿电阻和缓蚀剂浓度对模型计算的缓蚀ECL的影响。新的电致发光抑制机理可用于解释目前观察到的多种电致发光抑制剂，并有望发现更多的这类抑制剂，建立新的灵敏的电致发光检测方法。
Electrochemiluminescence (ECL) has been accepted by the analytical chemist as a powerful tool for detection of many inorganic and organic compounds. Ru(bpy)3 2+ has been the most popular ECL system, and many investigations have been focused on the application based on the enhancement or inhibition of Ru(bpy)3 2+ ECL system. However, not much attention has been paid to the theoretical investigation of this ECL system, especially to the inhibiting mechanism for the Ru(bpy)3 2+ ECL system. In the present study, many of the inorganic and organic compounds with electrochemical oxidation activity were found to strongly inhibit Ru(bpy)3 2+ ECL. To explain these inhibited ECL phenomena, a new "electrochemical oxidation inhibiting" mechanism has been proposed via the establishment of a corresponding model. The effects of applied potential, uncompensated resistance, and concentration of inhibitor on the inhibited ECL derived from the model have been verified by experiments. The new ECL inhibition mechanism can be commonly used to explain many kinds of inhibited ECL presently observed, and it is envisioned to result in finding of more inhibitors of this type and establishment of new sensitive ECL detection methods for them.