FDG PET of infection and inflammation
FDG PET of infection and inflammation
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DOI：
10.1148/rg.255045122
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发表时间：
2005-09-01
期刊：
影响因子：
5.5
通讯作者：
Palestro, CJ
中科院分区：
文献类型：
--
作者：
Love, C;Tomas, MB;Palestro, CJ
核医学在感染和炎症的评估中起着重要的作用。氟18氟脱氧葡萄糖（FDG）是一种容易获得的放射性示踪剂，可提供快速，灵敏的高分辨率断层扫描。在获得性免疫缺陷综合征患者中，FDG正电子发射断层扫描（PET）可以准确地帮助定位感染病灶，尤其有助于区分中枢神经系统淋巴瘤和弓形虫病。FDG PET还可以帮助定位不明原因发热（FUO）的来源，从而指导额外的测试。在肌肉骨骼系统中，FDG PET可以准确地帮助诊断脊柱骨髓炎，在炎性疾病如结节病和血管炎中，它似乎有助于确定疾病的程度和监测对治疗的反应。FDG PET在术后患者和关节假体或肿瘤失败的患者中可能用处有限。尽管如此，这种相对较新的成像技术有望有助于感染和炎症的诊断。FDG PET在评估FUO、脊柱骨髓炎、血管炎和结节病方面可能会越来越重要，甚至可能成为评价部分或全部这些病理状况的放射性核素成像程序的选择。(c)RSNA，2005年。
Nuclear medicine plays an important role in the evaluation of infection and inflammation. Fluorine 18 fluorodeoxyglucose (FDG) is a readily available radiotracer that offers rapid, exquisitely sensitive high-resolution tomography. In patients with acquired immunodeficiency syndrome, FDG positron emission tomography (PET) accurately helps localize foci of infection and is particularly useful for differentiating central nervous system lymphoma from toxoplasmosis. FDG PET can also help localize the source of fever of undetermined origin (FUO), thereby guiding additional testing. In the musculoskeletal system, FDG PET accurately helps diagnose spinal osteomyelitis, and in inflammatory conditions such as sarcoidosis and vasculitis, it appears to be useful for defining the extent of disease and monitoring response to treatment. FDG PET may be of limited usefulness in postoperative patients and in patients with a failed joint prosthesis or a tumor. Nevertheless, this relatively new imaging technique promises to be helpful in the diagnosis of infection and inflammation. FDG PET will likely assume increasing importance in assessing FUO, spinal osteomyelitis, vasculitis, and sarcoidosis and may even become the radionuclide imaging procedure of choice in the evaluation of some or all of these pathologic conditions. (c) RSNA, 2005.