Chinese Holstein Cattle Shows a Genetic Contribution from Native Asian Cattle Breeds: A Study of Shared Haplotypes and Demographic History
Chinese Holstein Cattle Shows a Genetic Contribution from Native Asian Cattle Breeds: A Study of Shared Haplotypes and Demographic History
复制标题
中国荷斯坦牛显示出亚洲本土牛品种的遗传贡献：共享单倍型和人口历史的研究
DOI：
10.5713/ajas.2011.10461
复制
发表时间：
2011-08-01
期刊：
影响因子：
--
通讯作者：
Han, Bo
中科院分区：
文献类型：
--
作者：
Ferreri, Miro;Gao, Jian;Han, Bo
中国荷斯坦牛品种是我国引进品种，与本土牛品种杂交而成。我们假设北京当地的中国荷斯坦牛种群与亚洲本土牛品种具有相同的单倍型，这是近期种群数量突然扩张的结果。我们还假设杂交和种群扩张留下了塑造该品种基因构成的痕迹。通过对来自北京的中国荷斯坦牛 (n = 41) 进行线粒体 DNA (mtDNA) 序列分析，并将其与已发表的 14 个亚洲品种（重点是中国本土牛品种）的 mtDNA 序列 (n = 293) 进行比较，对此进行了评估。在中国荷斯坦牛和亚洲本土牛之间发现了三种共有的单倍型。此外，中国荷斯坦牛的单倍型多样性较高（h = 0.9557），而核苷酸多样性较低（π = 0.0052），表明过去的种群瓶颈，随后出现种群快速增长。这些发现得到了田岛 D (-1.82085) 的显着负偏差、显性单倍型的星状模式和成对的支持。
The Chinese Holstein cattle breed, an introduced breed in China, has been crossbred with native cattle breeds. We hypothesised that the Chinese Holstein local population in Beijing share haplotypes with native Asian cattle breeds, the result of a sudden population expansion in the recent past. We also hypothesised that crossbreeding and population expansion left traces that shaped the genetic makeup of the breed. Evaluation of this was performed by mitochondrial DNA (mtDNA) sequence analysis of Chinese Holstein cattle from Beijing (n = 41) and a comparison of them with the published mtDNA sequences (n = 293) of 14 Asian breeds with an emphasis on Chinese native cattle breeds. Three shared common haplotypes between Chinese Holstein cattle and native Asian cattle were found. Moreover, a high level of haplotype diversity in Chinese Holstein cattle (h = 0.9557) and low nucleotide diversity (π = 0.0052) was found, indicating a past population bottleneck followed by rapid population growth. These findings are supported by the significantly negative deviation of Tajima's D (-1.82085), the star-like pattern of dominant haplotypes and the pairwise