Clinical significance of dental root canal microflora
Clinical significance of dental root canal microflora
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DOI：
10.1016/0300-5712(95)00042-9
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发表时间：
1996-01-01
影响因子：
4.4
通讯作者：
Drucker, DB
中科院分区：
文献类型：
--
作者：
Gomes, BPFA;Lilley, JD;Drucker, DB
目的：该小组先前的工作表明，疼痛与普雷沃菌属或消化链霉菌属的存在之间存在显著的关联。本研究的目的是对更广泛的根管进行微生物学检查，以确定是否有任何其他特定的牙髓症状或临床体征与个别细菌物种表现出特定的关联。方法：对70个根管进行微生物学检查，并收集临床数据以详细调查此类关联。在所研究的根管中，37个根管伴有疼痛，49个根管叩诊时有压痛，23个根管肿胀，6个根管有脓性渗出物，57个根管潮湿。从70.3%的疼痛根管和29.7%的无痛根管中分离出厌氧菌。（B）叩诊压痛和普雷沃菌属（Prevotella spp.）（c）肿胀与真杆菌属（P <0.01）、普雷沃氏菌属（P < 0.01）、Pstr.（d）脓性渗出液与F.坏死型（P < 0.01），Prev. loescheii、星座链球菌（Streptococcus constellatus）或拟杆菌属（Bacteroides spp.）(each结论：根管治疗的临床症状与细菌种类密切相关。
Objectives: Previous work by this group has shown that a significant association exists between pain and the presence of either Prevotella or Peptostreptococcus spp. in dental root canals, The aim of this study was to examine a more extensive series of canals microbiologically, to determine whether any other particular endodontic symptoms or clinical signs showed specific associations with individual bacterial species.Methods: Seventy root canals were examined microbiologically and clinical data collected to investigate in detail such associations.Results: Of the canals studied, 37 were associated with pain, 49 with tenderness to percussion, 23 with swelling, six with purulent exudate and 57 presented with wet root canals. Anaerobes were isolated from 70.3% of painful canals and from 29.7% of pain-free canals, Significant associations were found between (a) pain and either Prevotella spp. or peptostreptococci, both with P < 0.01; (b) tenderness to percussion and Prevotella spp. (P < 0.01) or anaerobes (P < 0.05); (c) swelling and Eubacterium spp, (P < 0.01), or with Prevotella spp, or Pstr. micros, both with P < 0.05; (d) purulent exudate and any one of F. necrophorum (P < 0.01), Prev. loescheii, Streptoccoccus constellatus or Bacteroides spp. (each P < 0.05); (e) wet canal and facultative anaerobes (P < 0.01), and any one of the genera of Eubacterium, Peptostreptococcus, Prevotella or Propionibacterium (each P < 0.05).Conclusion: It was concluded that several different endodontic clinical signs and symptoms are significantly associated with specific bacterial species.